Environmental Assessment of Enzyme Production and Purification

被引:22
作者
Becker, Martin [1 ]
Luetz, Stephan [1 ]
Rosenthal, Katrin [1 ]
机构
[1] TU Dortmund Univ, Dept Biochem & Chem Engn, Chair Bioproc Engn, D-44227 Dortmund, Germany
关键词
E factor; biocatalysis; green chemistry; cGAS; bioprocess engineering; life cycle assessment; GREEN;
D O I
10.3390/molecules26030573
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The importance of bioprocesses has increased in recent decades, as they are considered to be more sustainable than chemical processes in many cases. E factors can be used to assess the sustainability of processes. However, it is noticeable that the contribution of enzyme synthesis and purification is mostly neglected. We, therefore, determined the E factors for the production and purification of 10 g enzymes. The calculated complete E factor including required waste and water is 37,835 g(waste)center dot g(enzyme)(-1). This result demonstrates that the contribution of enzyme production and purification should not be neglected for sustainability assessment of bioprocesses.
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页数:10
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