Imaging of Iris lesions with high-speed optical coherence tomography

被引：15
作者：
Bakri, Sophie J.
Singh, Arun D.
Lowder, Careen Y.
Chalita, Maria Regina
Li, Yan
Izatt, Joseph A.
Rollins, Andrew M.
Huang, David
机构：
[1] Cleveland Clin Fdn, Cole Eye Inst, Cleveland, OH 44195 USA
[2] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA
来源：
OPHTHALMIC SURGERY LASERS & IMAGING | 2007年 / 38卷 / 01期
关键词：
IN-VIVO;
D O I：
10.3928/15428877-20070101-04
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
BACKGROUND AND OBJECTIVES: To image and measure iris tumors with optical coherence tomography (OCT). PATIENTS AND METHODS: High-speed (2,0004,000 axial-scan/sec and 4-16 frames/sec) 1.3-micron wavelength anterior segment OCT prototypes were used to image 6 eyes of 6 patients with a variety of iris lesions, including focal iris nevus, diffuse iris nevus, amelanotic iris nevus, iris melanocytosts, and iris melanoma. OCT images were compared with slit-lamp photography and ultrasound biomicroscopy. RESULTS: OCT at 1.3-micron wavelength couldpenetrate the full thickness of the iris lesions and allow three-dimensional measurement of lesion size. Internal reflectivity is correlated with pigmentation. OCT is a convenient non-contact method that provides imaging of the clinically important angle structures (scleral spur and angle recess). CONCLUSIONS: OCT is a new imaging modality that complements slit-lamp photography and ultrasound biomicroscopy for serial evaluation of iris lesions.
引用
收藏
页码：27 / 34
页数：8
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