Association of British Clinical Diabetologists and Renal Association guidelines on the detection and management of diabetes post solid organ transplantation

被引：42

作者：

Chowdhury, Tahseen A. ^{[1
]}

Wahba, Mona ^{[2
]}

Mallik, Ritwika ^{[1
]}

Peracha, Javeria ^{[3
]}

Patel, Dipesh ^{[4
]}

De, Parijat ^{[5
]}

Fogarty, Damian ^{[6
]}

Frankel, Andrew ^{[7
]}

Karalliedde, Janaka ^{[8
,9
]}

Mark, Patrick B. ^{[10
]}

Montero, Rosa M. ^{[9
]}

Pokrajac, Ana ^{[11
]}

Zac-Varghese, Sagen ^{[12
]}

Bain, Stephen C. ^{[13
]}

Dasgupta, Indranil ^{[14
,15
]}

Banerjee, Debasish ^{[16
,17
]}

Winocour, Peter ^{[18
]}

Sharif, Adnan ^{[19
]}

机构：

[1] Royal London Hosp, London E1 1BB, England

[2] St Helier Hosp, London, England

[3] Univ Hosp Birmingham NHS Trust, Birmingham, W Midlands, England

[4] UCL, Diabet & Endocrinol, Royal Free NHS Fdn Trust, London, England

[5] City Hosp, Birmingham, W Midlands, England

[6] Belfast Hlth & Social Care Trust, Belfast, Antrim, North Ireland

[7] Imperial Coll Healthcare NHS Trust, London, England

[8] Guys & St Thomas NHS Fdn Trust, London, England

[9] Kings Coll London, London, England

[10] Univ Glasgow, Glasgow, Lanark, Scotland

[11] West Hertfordshire Hosp NHS Trust, Watford, England

[12] Lister Hosp, ENHIDE, Stevenage, Herts, England

[13] Univ Swansea, Swansea, W Glam, Wales

[14] Heartlands Hosp, Birmingham, W Midlands, England

[15] Warwick Med Sch, Warwick, England

[16] St Georges Univ Hosp NHS Fdn Trust, Renal & Transplant Unit, London, England

[17] St Georges Univ London, MCSRI, London, England

[18] QE2 Hosp Welwyn, ENHIDE, Welwyn Garden City, Herts, England

[19] Univ Hosp Birmingham, Birmingham, W Midlands, England

来源：

DIABETIC MEDICINE | 2021年 / 38卷 / 06期

关键词：

D O I：

10.1111/dme.14523

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Post-transplant diabetes mellitus (PTDM) is common after solid organ transplantation (SOT) and associated with increased morbidity and mortality for allograft recipients. Despite the significant burden of disease, there is a paucity of literature with regards to detection, prevention and management. Evidence from the general population with diabetes may not be translatable to the unique context of SOT. In light of emerging clinical evidence and novel anti-diabetic agents, there is an urgent need for updated guidance and recommendations in this high-risk cohort. The Association of British Clinical Diabetologists (ABCD) and Renal Association (RA) Diabetic Kidney Disease Clinical Speciality Group has undertaken a systematic review and critical appraisal of the available evidence. Areas of focus are; (1) epidemiology, (2) pathogenesis, (3) detection, (4) management, (5) modification of immunosuppression, (6) prevention, and (7) PTDM in the non-renal setting. Evidence-graded recommendations are provided for the detection, management and prevention of PTDM, with suggested areas for future research and potential audit standards. The guidelines are endorsed by Diabetes UK, the British Transplantation Society and the Royal College of Physicians of London. The full guidelines are available freely online for the diabetes, renal and transplantation community using the link below. The aim of this review article is to introduce an abridged version of this new clinical guideline ( ).

引用

页数：18

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