Differential role of TRP channels in prostate cancer

被引：31
作者：
Prevarskaya, N. [1 ]
Flourakis, M.
Bidaux, G.
Thebault, S.
Skryma, R.
机构：
[1] INSERM, Equipe Labellisee Ligue Natl Contre Canc, U800, F-59655 Villeneuve Dascq, France
[2] Univ Sci & Tech Lille Flandres Artois, F-59655 Villeneuve Dascq, France
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 2007年 / 35卷
关键词：
apoptosis; calcium; cell differentiation; cell proliferation; prostate cancer; transient receptor potential channel (TRP channel);
D O I：
10.1042/BST0350133
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A major clinical problem with PC (prostate cancer) is the cell's ability to survive and proliferate upon androgen withdrawal. indeed, deregulated cell differentiation and proliferation, together with the suppression of apoptosis, provides the condition for abnormal tissue growth. Here, we examine the differential role of TRP (transient receptor potential) channels in the control of Ca2+ homoeostasis and growth of PC cells.
引用
收藏
页码：133 / 135
页数：3
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