Isolation of 5′-O-sulfamyladenosine and related 3′-O-β-glucosylated adenosines from the nucleocidin producer Streptomyces calvus

被引：13

作者：

Feng, Xuan ^{[1
]}

Bello, Davide ^{[1
]}

O'Hagan, David ^{[1
]}

机构：

[1] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland

来源：

RSC ADVANCES | 2021年 / 11卷 / 10期

基金：

英国工程与自然科学研究理事会;

关键词：

Metabolites;

D O I：

10.1039/d1ra00235j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The isolation of three adenosine based metabolites 6-8 from Streptomyces calvus is reported. The metabolites are structurally related to the fluorine containing antibiotic nucleocidin 1 and two recently identified glycosylated fluoroadenosines 2 and 3, however in this case the three metabolites do not contain a fluorine, suggesting that the biosynthetic enzymes to the fluorometabolites also process their non-fluorinated counterparts.

引用

页码：5291 / 5294

页数：4

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