Cutaneous metastases of papillary renal cell carcinoma: A case report and review of the literature

被引：1

作者：

Cardwell, Leah A. ^{[1
]}

Bender, Nicole R. ^{[1
]}

Sokumbi, Olayemi ^{[1
]}

机构：

[1] Med Coll Wisconsin, Dept Dermatol, 8701 W Watertown Plank Rd, Milwaukee, WI 53226 USA

来源：

JOURNAL OF CUTANEOUS PATHOLOGY | 2019年 / 46卷 / 12期

关键词：

cutaneous metastases; papillary; renal cell carcinoma; solid organ malignancy;

D O I：

10.1111/cup.13546

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Papillary renal cell carcinoma (RCC) is an uncommon subtype of RCC that is typically encountered at early stages and has a high survival rate. Histopathology typically shows well-defined papillary architecture with tumor cells lining fibrovascular cores and can be further subdivided into type 1 and type 2 tumors based on cytology and genetic basis. Type 1 tumors have a single layer of basophilic cells and low nuclear atypia, while type 2 tumors have a pseudostratified layer of eosinophilic cells and high nuclear atypia. Some tumors have overlapping features of both types. We present a unique case of cutaneous metastases of papillary RCC with typical papillary architecture in the dermis and review the literature on this rare entity.

引用

页码：960 / 964

页数：5

共 12 条

[1]

Alshenawy HA, 2015, PATHOL ONCOL RES, V21, P893, DOI [10.1007/s12253-015-9898-7, 10.1016/j.jmau.2015.01.003]

[2] Erythematous Patches and Plaques on the Chest With Induration of the Breasts Metastatic papillary RCC in dermal lymphatics. [J].

Balagula, Yevgeniy ;

Lopez, Natalia Jaimes ;

Busam, Klaus J. ;

Quigley, Elizabeth A. .

ARCHIVES OF DERMATOLOGY, 2011, 147 (10) :1215-1220

[3]

Delahunt B, 1997, MODERN PATHOL, V10, P537

[4]

Hirsch Michelle S, 2015, Surg Pathol Clin, V8, P587, DOI 10.1016/j.path.2015.09.003

[5] Rising incidence of small renal masses: A need to reassess treatment effect [J].

Hollingsworth, John M. ;

Miller, David C. ;

Daignault, Stephanie ;

Hollenbeck, Brent K. .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2006, 98 (18) :1331-1334

[6]

Howlader N, 2020, SEER CANC STAT REV 1

[7] Expression of p63 in cutaneous metastases [J].

Kanitakis, Jean ;

Chouvet, Brigitte .

AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2007, 128 (05) :753-758

[8] CUTANEOUS METASTASES IN PATIENTS WITH METASTATIC CARCINOMA - A RETROSPECTIVE STUDY OF 4020 PATIENTS [J].

LOOKINGBILL, DP ;

SPANGLER, N ;

HELM, KF .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1993, 29 (02) :228-236

[9] Hereditary leiomyomatosis and renal cell cancer (HLRCC): renal cancer risk, surveillance and treatment [J].

Menko, Fred H. ;

Maher, Eamonn R. ;

Schmidt, Laura S. ;

Middelton, Lindsay A. ;

Aittomaki, Kristiina ;

Tomlinson, Ian ;

Richard, Stephane ;

Linehan, W. Marston .

FAMILIAL CANCER, 2014, 13 (04) :637-644

[10] Neutrophils in the Tumor Microenvironment [J].

Powell, Davalyn R. ;

Huttenlocher, Anna .

TRENDS IN IMMUNOLOGY, 2016, 37 (01) :41-52

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