Self-medication with steroids in inflammatory bowel disease

被引:9
作者
Filipe, Virginie [1 ,2 ]
Allen, Patrick B. [3 ]
Peyrin-Biroulet, Laurent [1 ,2 ]
机构
[1] Univ Lorraine, Nancy Univ Hosp, Inserm U954, Allee Morvan, F-54511 Vandoeuvre Les Nancy, France
[2] Univ Lorraine, Nancy Univ Hosp, Dept Hepatogastroenterol, Allee Morvan, F-54511 Vandoeuvre Les Nancy, France
[3] Ulster Hosp, Dept Gastroenterol, Belfast, Antrim, North Ireland
关键词
Inflammatory bowel disease; Self-medication; Steroids; EVIDENCE-BASED CONSENSUS; ULCERATIVE-COLITIS; CROHNS-DISEASE; MANAGEMENT; PRESCRIPTION; PREVALENCE; DIAGNOSIS; THERAPY; IMPACT; TRIAL;
D O I
10.1016/j.dld.2015.10.010
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: The self-prescribing rates of corticosteroids in inflammatory bowel disease (IBD) patients treated with biologicals are unknown. Aim: To investigate the frequency and modalities of self-medication with steroids in adult IBD patients. Methods: Patients with IBD who attended Nancy University Hospital between November 2012 and May 2013 were included in the study. Patients were interviewed using an 11 item questionnaire. Results: 100 patients participated in the survey. In total 15 patients (15%) had already used corticosteroids without medical prescription since their IBD diagnosis and 4 patients of them (27%) used steroids as self-medication while on anti-TNF treatment. The mean total duration of corticosteroid treatment was 24 days (range 1.5-105). In total 4 patients (27%) used corticosteroids more than 10 times without medical prescription (range 1-20). The two main reasons were the need for quick relief of symptoms (n = 6) and the unwillingness to consult a physician (n = 3). Conclusion: A relatively high proportion of patients with IBD use corticosteroids without medical prescription. Due to their side effects, self-medication may include 'steroid dependency' as it may reflect uncontrolled disease. As steroids have significant side effects and patients may have active disease it is important to counsel patients and to monitor their self-prescribing patterns in IBD patients. (C) 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:23 / 26
页数:4
相关论文
共 19 条
[1]  
[Anonymous], 2011, ROL PHARM SELF CAR S
[2]   Over-the-counter migration of steroid use: impact on the eye [J].
Bielory, Brett ;
Bielory, Leonard .
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 14 (05) :471-476
[3]   Prevalence of self-medication for skin diseases: a systematic review [J].
Correa-Fissmer, Mariane ;
Mendonca, Mariana Gaspar ;
Martins, Anesio Henrique ;
Galato, Dayani .
ANAIS BRASILEIROS DE DERMATOLOGIA, 2014, 89 (04) :625-630
[4]   The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Current management [J].
Dignass, A. ;
Van Assche, G. ;
Lindsay, J. O. ;
Lemann, M. ;
Soderholm, J. ;
Colombel, J. F. ;
Danese, S. ;
D'Hoore, A. ;
Gassull, M. ;
Gomollon, F. ;
Hommes, D. W. ;
Michetti, P. ;
O'Morain, C. ;
Oresland, T. ;
Windsor, A. ;
Stange, E. F. ;
Travis, S. P. L. .
JOURNAL OF CROHNS & COLITIS, 2010, 4 (01) :28-62
[5]   Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 1: Definitions and diagnosis [J].
Dignass, Axel ;
Eliakim, Rami ;
Magro, Fernando ;
Maaser, Christian ;
Chowers, Yehuda ;
Geboes, Karel ;
Mantzaris, Gerassimos ;
Reinisch, Walter ;
Colombel, Jean-Frederic ;
Vermeire, Severine ;
Travis, Simon ;
Lindsay, James O. ;
Van Assche, Gert .
JOURNAL OF CROHNS & COLITIS, 2012, 6 (10) :965-990
[6]   Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management (Publication with Expression of Concern) [J].
Dignass, Axel ;
Lindsay, James O. ;
Sturm, Andreas ;
Windsor, Alastair ;
Colombel, Jean-Frederic ;
Allez, Mathieu ;
D'Haens, Gert ;
D'Hoore, Andre ;
Mantzaris, Gerassimos ;
Novacek, Gottfried ;
Oeresland, Tom ;
Reinisch, Walter ;
Sans, Miquel ;
Stange, Eduard ;
Vermeire, Severine ;
Travis, Simon ;
Van Assche, Gert .
JOURNAL OF CROHNS & COLITIS, 2012, 6 (10) :991-1030
[7]   E-health empowers patients with ulcerative colitis: a randomised controlled trial of the web-guided 'Constant-care' approach [J].
Elkjaer, Margarita ;
Shuhaibar, Mary ;
Burisch, Johan ;
Bailey, Yvonne ;
Scherfig, Hanne ;
Laugesen, Birgit ;
Avnstrom, Soren ;
Langholz, Ebbe ;
O'Morain, Colm ;
Lynge, Elsebeth ;
Munkholm, Pia .
GUT, 2010, 59 (12) :1652-1661
[8]   Risks of Self-Medication Practices [J].
Esperanza Ruiz, Maria .
CURRENT DRUG SAFETY, 2010, 5 (04) :315-323
[9]   Use of non prescription drugs for acute dermatoses.: A prospective study of III hospitalized patients [J].
Estève, E ;
Ah-Toye, C ;
Nseir, A ;
Martin, L .
ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2005, 132 (04) :372-373
[10]   The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study [J].
Faubion, WA ;
Loftus, EV ;
Harmsen, WS ;
Zinsmeister, AR ;
Sandborn, WJ .
GASTROENTEROLOGY, 2001, 121 (02) :255-260