A time-varying SIRD model for the COVID-19 contagion in Italy

被引:123
作者
Calafiore, Giuseppe C. [1 ,3 ]
Novara, Carlo [1 ]
Possieri, Corrado [2 ]
机构
[1] Politecn Torino, Dipartimento Elettron & Telecomunicaz, I-10129 Turin, Italy
[2] Consiglio Nazl Ric IASI CNR, Ist Anal Sistemi Informat A Ruberti, I-00185 Rome, Italy
[3] CNR, Inst Elect Comp & Telecommun Engn, Turin, Italy
关键词
Covid-19; SIR models; Lasso; Contagion modeling; EPIDEMIC; NETWORK;
D O I
10.1016/j.arcontrol.2020.10.005
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
The purpose of this work is to give a contribution to the understanding of the COVID-19 contagion in Italy. To this end, we developed a modified Susceptible-Infected-Recovered-Deceased (SIRD) model for the contagion, and we used official data of the pandemic for identifying the parameters of this model. Our approach features two main non-standard aspects. The first one is that model parameters can be time-varying, allowing us to capture possible changes of the epidemic behavior, due for example to containment measures enforced by authorities or modifications of the epidemic characteristics and to the effect of advanced antiviral treatments. The time-varying parameters are written as linear combinations of basis functions and are then inferred from data using sparse identification techniques. The second non-standard aspect resides in the fact that we consider as model parameters also the initial number of susceptible individuals, as well as the proportionality factor relating the detected number of positives with the actual (and unknown) number of infected individuals. Identifying the model parameters amounts to a non-convex identification problem that we solve by means of a nested approach, consisting in a one-dimensional grid search in the outer loop, with a Lasso optimization problem in the inner step.
引用
收藏
页码:361 / 372
页数:12
相关论文
共 26 条
  • [1] Bailey N.T.J., 1975, The Mathematical Theory of Infectious Diseases and its Applications, V2nd
  • [2] Bohner M., 2018, TECHNICAL REPORT
  • [3] Brauer Fred, 2017, Infect Dis Model, V2, P113, DOI 10.1016/j.idm.2017.02.001
  • [4] Caccavo D., 2020, CHINESE ITALIAN COVI, DOI 10.1101/2020.03.19.20039388
  • [5] Sparse identification of posynomial models
    Calafiore, Giuseppe C.
    El Ghaoui, Laurent M.
    Novara, Carlo
    [J]. AUTOMATICA, 2015, 59 : 27 - 34
  • [6] Casella F., 2020, ARXIV200306967
  • [7] A novel sub-epidemic modeling framework for short-term forecasting epidemic waves
    Chowell, Gerardo
    Tariq, Amna
    Hyman, James M.
    [J]. BMC MEDICINE, 2019, 17 (01)
  • [8] Chowell Gerardo, 2017, Infect Dis Model, V2, P379, DOI 10.1016/j.idm.2017.08.001
  • [9] Optimal control of SIR epidemic model with state dependent switching cost index
    Di Giamberardino, Paolo
    Iacoviello, Daniela
    [J]. BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 2017, 31 : 377 - 380
  • [10] DiBernardo M., 2020, IEEE CSS ONL WORKSH