Two new monoterpene glucosides from Xanthium strumarium subsp. sibiricum with their anti-inflammatory activity

被引:7
作者
Jiang, Hai [1 ]
Xing, Xudong [1 ]
Yan, Meiling [1 ]
Guo, Xinyue [1 ]
Yang, Lin [1 ]
Yang, Liu [1 ]
机构
[1] Heilongjiang Univ Chinese Med, Key Lab Chinese Mat Med, Minist Educ, Harbin, Heilongjiang, Peoples R China
基金
中国国家自然科学基金;
关键词
X; strumarium; monoterpene glucosides; antiinflammatory activity; CONSTITUENTS; EXTRACT; ROOTS; CAVANILLESII; GLYCOSIDES;
D O I
10.1080/14786419.2018.1479701
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1??M, respectively.
引用
收藏
页码:3383 / 3388
页数:6
相关论文
共 19 条
[1]   Sesquiterpene lactones from the aerial parts of Xanthium sibiricum and their cytotoxic effects on human cancer cell lines [J].
Bui, Van-Binh ;
Liu, Shu-Ting ;
Zhu, Jing-Jing ;
Xiong, Juan ;
Zhao, Yun ;
Yang, Guo-Xun ;
Xia, Gang ;
Hu, Jin-Feng .
PHYTOCHEMISTRY LETTERS, 2012, 5 (03) :685-689
[2]   A new naphthoquinone and other antibacterial constituents from the roots of Xanthium sibiricum [J].
Chen, Wen-Hao ;
Liu, Wen-Jie ;
Wang, Yan ;
Song, Xiao-Ping ;
Chen, Guang-Ying .
NATURAL PRODUCT RESEARCH, 2015, 29 (08) :739-744
[3]   A new acyclic monoterpene glucoside from Viscum album ssp album [J].
Deliorman, D ;
Çalis, I ;
Ergun, F .
FITOTERAPIA, 2001, 72 (02) :101-105
[4]   Anti-ulcerogenic activity of xanthanolide sesquiterpenes from Xanthium cavanillesii in rats [J].
Favier, LS ;
María, AOM ;
Wendel, GH ;
Borkowski, EJ ;
Giordano, OS ;
Pelzer, L ;
Tonn, CE .
JOURNAL OF ETHNOPHARMACOLOGY, 2005, 100 (03) :260-267
[5]   [Rh2(OCOCF3)4] as an auxiliary chromophore in chiroptical studies on steroidal alcohols [J].
Frelek, J ;
Szczepek, WJ .
TETRAHEDRON-ASYMMETRY, 1999, 10 (08) :1507-1520
[6]   CIRCULAR-DICHROISM .93. DETERMINATION OF THE ABSOLUTE-CONFIGURATION OF ALCOHOLS, OLEFINS, EPOXIDES, AND ETHERS FROM THE CD OF THEIR INSITU COMPLEXES WITH [RH2(O2CCF3)4] [J].
GERARDS, M ;
SNATZKE, G .
TETRAHEDRON-ASYMMETRY, 1990, 1 (04) :221-236
[7]   Four New Glycosides from the Fruit of Xanthium sibiricum Patr. [J].
Jiang, Hai ;
Yang, Liu ;
Liu, Chang ;
Hou, Hui ;
Wang, Qiuhong ;
Wang, Zhibin ;
Yang, Bingyou ;
Kuang, Haixue .
MOLECULES, 2013, 18 (10) :12464-12473
[8]   Chemical constituents from the roots of Xanthium sibiricum [J].
Kan, Suqin ;
Chen, Guangying ;
Han, Changri ;
Chen, Zhong ;
Song, Xinming ;
Ren, Ming ;
Jiang, Hong .
NATURAL PRODUCT RESEARCH, 2011, 25 (13) :1243-1249
[9]   (-)-Xanthienopyran, a new inhibitor of superoxide anion generation by activated neutrophils, and further constituents of the seeds of Xanthium strumarium [J].
Lee, Chia-Lin ;
Huang, Po-Ching ;
Hsieh, Pei-Wen ;
Hwang, Tsong-Long ;
Hou, Yu-Yi ;
Chang, Fang-Rong ;
Wu, Yang-Chang .
PLANTA MEDICA, 2008, 74 (10) :1276-1279
[10]   2 TOXIC KAURENE GLYCOSIDES FROM THE BURRS OF XANTHIUM-PUNGENS [J].
MACLEOD, JK ;
MOELLER, PDR ;
FRANKE, FP .
JOURNAL OF NATURAL PRODUCTS, 1990, 53 (02) :451-455