Proton beam therapy in pediatric radiotherapy

被引：18

作者：

Habrand, J-L ^{[1
,2
]}

Bolle, S. ^{[1
,3
]}

Datchary, J. ^{[1
,2
]}

Alapetite, C. ^{[1
,3
]}

Petras, S. ^{[4
]}

Helfre, S. ^{[1
,3
]}

Feuvret, L. ^{[1
,5
]}

Calugaru, V. ^{[1
,3
]}

De Marzi, L. ^{[1
]}

Bouyon-Monteau, A. ^{[3
]}

Dendale, R. ^{[1
,3
]}

Kalifa, C. ^{[6
]}

Grill, J. ^{[6
]}

Doz, F. ^{[7
]}

机构：

[1] Inst Curie a Orsay ICPO, Ctr Protontherapie, F-91898 Orsay, France

[2] Inst Gustave Roussy, Dept Radiotherapie, F-94805 Villejuif, France

[3] Inst Curie, Dept Radiotherapie, F-75248 Paris, France

[4] Inst Curie, Dept Imagerie, F-75248 Paris 05, France

[5] Hop La Pitie Salpetriere, AP HP, Dept Radiotherapie, F-75651 Paris 13, France

[6] Inst Gustave Roussy, Dept Pediat, F-94805 Villejuif, France

[7] Inst Curie, Dept Pediat, F-75248 Paris 05, France

来源：

CANCER RADIOTHERAPIE | 2009年 / 13卷 / 6-7期

关键词：

Radiation therapy; Proton beam therapy; Pediatrics; Local control; Side effects; Sequelae; CENTRAL-NERVOUS-SYSTEM; RADIATION-THERAPY; X-RAY; CRANIOSPINAL IRRADIATION; POSTERIOR-FOSSA; POTENTIAL ROLE; BRAIN-TUMORS; 2ND CANCERS; MEDULLOBLASTOMA; CHILDHOOD;

D O I：

10.1016/j.canrad.2009.07.001

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pediatric tumors still represent a formidable challenge despite the considerable therapeutical advances that have been reported for the past 30 years. This is largely related with the untowards side-effects of local therapy that are still acknowledged as the "price for cure". In this setting, Proton therapy a sophisticated radiotherapeutical modality seems to represent a real breakthrough due to its unique ability to spare close and distant normal organs compared with modern photons techniques. We summarize in this paper current clinical and dosimetrical evidences including an update of the Orsay series on 108 children. (C) 2009 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.

引用

页码：550 / 555

页数：6

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