Chemical composition of Schinus areira essential oil and antimicrobial action against Staphylococcus aureus

被引:15
作者
Cutro, Andrea C. [1 ,2 ,6 ]
Castelli, M. Victoria [3 ]
Lopez, Silvia N. [3 ]
Rosales, Manuel A. [4 ]
Hollmann, Axel [1 ,5 ,6 ]
Rodriguez, Sergio A. [4 ,6 ]
机构
[1] UNSE, Lab Compuestos Bioact, Ctr Invest Biofis Aplicada & Alimentos CIBAAL, CONICET, Santiago Del Estero, Argentina
[2] UNSE, Fac Ciencias Med, Santiago Del Estero, Argentina
[3] Univ Nacl Rosario, CONICET, Farmacognosia, Fac Ciencias Bioquim & Farmaceut, Rosario, Santa Fe, Argentina
[4] UNSE, Fac Agron & Agroind, Santiago Del Estero, Argentina
[5] Univ Nacl Quilmes, DCyT, Mol Microbiol Lab, Bernal, Argentina
[6] Consejo Nacl Invest Cient & Tecn, Santiago Del Estero, Argentina
关键词
Aguaribay; essential oil; Staphylococcus aureus; 1-epi-cadinol; antibacterial activity; zeta potential; MOLLE L; ANTIOXIDANT; LEAVES;
D O I
10.1080/14786419.2019.1675065
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The antimicrobial activities of plant extracts have formed the basis of many alternative medicines. In this context, the genus Schinus L. (Anacardiaceae), exhibits many traditional uses in medicine. However, a few studies on the antimicrobial properties of Schinus areira essential oils were conducted. The essential oil from S. areira leaves from Santiago del Estero was obtained by hydrodistillation and twenty-eight compounds were identified using CG-MS-EI spectrometry. The sesquiterpenoid alcohol 1-epi-cadinol was the major compound, followed by ?-cadinene, alloaromadendrene, ?-pinene, ?-caryophyllene, and ?-cadinene. The essential oil obtained exhibited antimicrobial activity against Staphylococcus aureus, showing a bacteriostatic activity at 64??g/mL and bacteriolytic activity at 256??g/mL; in contrast, non antibacterial effect was observed in Escherichia coli in the assayed conditions. The antibacterial activity was accompanied by significant changes in Zeta potential on the S. aureus surface. The data obtained suggest that the essential oil of S.areira leaves presents potential use in pharmaceutical industries.
引用
收藏
页码:2931 / 2936
页数:6
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