Metastatic Mucinous Adenocarcinoma Presenting as Cerebellopontine Angle Tumor

被引:0
作者
Thavara, Binoy Damodar [1 ]
Rajagopalawarrier, Bijukrishnan [1 ]
机构
[1] Govt Med Coll, Dept Neurosurg, Trichur 680596, Kerala, India
关键词
Cerebellopontine angle tumor; metastasis; mucinous adenocarcinoma;
D O I
10.4103/jss.JSS_32_19
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Intracranial posterior fosse metastasis is a common entity. Metastatic mucinous adenocarcinoma presenting as cerebellopontine angle (CPA) tumor is very rare. The authors presented a 47-year-old female patient with right CPA tumor. The magnetic resonance imaging brain showed a heterogeneous contrast-enhancing ducal-based extra-axial right CPA lesion involving the right cerebellar hemisphere, internal auditory meatus, and posterior surface of the right petrous bone. The patient underwent surgery, and subtotal resection of the tumor was done. Histology of the tumor was metastasis from a mucinous adenocarcinoma. Contrast-enhanced computed tomography scan of the abdomen and pelvis, ultrasound of the thyroid, chest X-ray, and thyroid function tests were normal. Carbohydrate antigen (CA) 19-9 was 949.37 TJ/mL, serum carcinoembryonic antigen (CEA) was 48.17 ng/mL, and CA-125 was 8.20 U/mL. In view of the raised CA 19-9 and CEA, primary malignancy was believed to be arising from the pancreas or from the gastrointestinal tract, though the definitive diagnosis of primary malignancy was not made. Although rare, metastatic mucinous adenocarcinoma should be kept in the differential diagnosis of CPA lesions. Even though the tumor is radiologically mimicking as CPA schwannoma, the absence of hearing abnormality should raise the suspicion for other diagnoses.
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页码:63 / 66
页数:4
相关论文
共 10 条
[1]   Solitary Metastasis to the Facial/Vestibulocochlear Nerve Complex: Case Report and Review of the Literature [J].
Ariai, M. Shafie ;
Eggers, Scott D. ;
Giannini, Caterina ;
Driscoll, Colin L. W. ;
Link, Michael J. .
WORLD NEUROSURGERY, 2015, 84 (04) :1178.e15-1178.e18
[2]   The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal [J].
Ballehaninna, Umashankar K. ;
Chamberlain, Ronald S. .
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2012, 3 (02) :105-119
[3]  
주원일, 2003, [Journal of Korean Neurosurgical Society, 대한신경외과학회지], V34, P252
[4]  
MACH JP, 1975, B CANCER, V62, P445
[5]  
Maksimovic Siniga, 2007, Med Arh, V61, P26
[6]  
Moffat D A, 1995, Clin Oncol (R Coll Radiol), V7, P28, DOI 10.1016/S0936-6555(05)80632-6
[7]  
Perkins GL, 2003, AM FAM PHYSICIAN, V68, P1075
[8]  
Sarrazin JL, 2000, J RADIOL, V81, P675
[9]   CA 19-9: Biochemical and Clinical Aspects [J].
Scara, Salvatore ;
Bottoni, Patrizia ;
Scatena, Roberto .
ADVANCES IN CANCER BIOMARKERS: FROM BIOCHEMISTRY TO CLINIC FOR A CRITICAL REVISION, 2015, 867 :247-260
[10]  
YUH WTC, 1993, AM J NEURORADIOL, V14, P99