Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department A retrospective cohort study

被引：10

作者：

Kim, Kwan Jae ^{[1
]}

Min, Jin Hong ^{[2
,3
]}

Yoo, Insool ^{[1
,2
]}

Kim, Seung Whan ^{[1
,2
]}

Lee, Jinwoong ^{[1
]}

Ryu, Seung ^{[1
]}

You, Yeon Ho ^{[1
]}

Park, Jung Soo ^{[1
,2
]}

Jeong, Won Joon ^{[1
]}

Cho, Yong Chul ^{[1
]}

Oh, Se Kwang ^{[3
]}

In, Yong Nam ^{[3
]}

Ahn, Hong Joon ^{[1
]}

Kang, Chang Shin ^{[1
]}

Kyung, Hyunwoo ^{[4
]}

Lee, Byung Kook ^{[5
,6
]}

Lee, Dong Hun ^{[6
]}

Lee, Dong Hoon ^{[7
]}

机构：

[1] Chungnam Natl Univ Hosp, Dept Emergency Med, Daejeon, South Korea

[2] Chungnam Natl Univ, Dept Emergency Med, Coll Med, 266 Munhwa Ro, Daejeon, South Korea

[3] Chungnam Natl Univ, Sejong Hosp, Dept Emergency Med, 7 Bodam Ro, Sejong, South Korea

[4] Chungnam Natl Univ, Sejong Hosp, Dept Plast Surg, 7 Bodam Ro, Sejong, South Korea

[5] Chonnam Natl Univ, Dept Emergency Med, Sch Med, Gwangju, South Korea

[6] Chonnam Natl Univ Hosp, Dept Emergency Med, 42 Jebong Ro, Gwangju, South Korea

[7] Chung Ang Univ, Dept Emergency Med, Coll Med, 47 Heukseok Ro, Seoul, South Korea

来源：

MEDICINE | 2021年 / 100卷 / 03期

关键词：

edema; negative pressure wound therapy; skin necrosis; snakebites; wound infection; VACUUM-ASSISTED CLOSURE; MECHANISM; EFFICACY; CELLS; MNSOD; BITE; NPWT;

D O I：

10.1097/MD.0000000000024290

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites. Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results. Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001). These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.

引用

页数：8

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