Two surgical cases of thymic MALT lymphoma associated with multiple lung cysts: possible association with Sjogren's syndrome

被引:10
作者
Arai, Hiromasa [1 ]
Tajiri, Michihiko [1 ]
Kaneko, Shotaro [1 ]
Kushida, Yoshihiro [1 ]
Ando, Kohei [1 ]
Tachibana, Takayoshi [5 ]
Umeda, Shigeaki [2 ]
Okudela, Koji [2 ]
Komatsu, Shigeru [3 ]
Masuda, Munetaka [4 ]
机构
[1] Kanagawa Cardiovasc & Resp Ctr, Dept Gen Thorac Surg, Kanazawa Ku, 6-16-1 Tomiokahigashi, Yokohama, Kanagawa 2368651, Japan
[2] Yokohoma City Univ, Grad Sch Med, Dept Pathol, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan
[3] Kanagawa Cardiovasc & Resp Ctr, Dept Resp Med, Kanazawa Ku, 6-16-1 Tomiokahigashi, Yokohama, Kanagawa 2368651, Japan
[4] Yokohoma City Univ, Grad Sch Med, Dept Surg, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan
[5] Yokohoma City Univ, Dept Hematol & Clin Immunol, Grad Sch Med, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan
关键词
MALT lymphoma; Thymus; Sjogren's syndrome (S[!text type='jS']jS[!/text]); Lung cyst; Video-assisted thoracoscopic; surgery (VATS); B-CELL LYMPHOMA; TISSUE;
D O I
10.1007/s11748-016-0652-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thymic mucosa-associated lymphoid tissue (MALT) lymphoma is rare. Sjogren's syndrome (SjS) has strong association with thymic MALT lymphoma but the exact etiology is unknown. On the other hand, SjS is characterized by the complication of various lung manifestations, including lung cysts. The mechanism for these lesions is also unknown. But the underlying SjS could result in MALT lymphoma with lung cysts. Herein, we demonstrate two surgical cases of thymic MALT lymphoma associated with multiple lung cysts and the characterization of this rare tumor. During surgery, the tumors were found to be well capsuled and had no adhesion or invasion to the surrounding tissues consistent with its characteristics of low grade malignancy. When thymic MALT lymphoma is suspected clinically, video-assisted thoracoscopic surgery might be the best approach for diagnosis. We propose that radiological findings of a thymic tumor along with lung cysts are an indication of thymic MALT lymphoma.
引用
收藏
页码:229 / 234
页数:6
相关论文
共 12 条
[1]   Amyloid-associated cystic lung disease in primary Sjogren's syndrome [J].
Baqir, Misbah ;
Kluka, Elizabeth M. ;
Aubry, Marie-Christine ;
Hartman, Thomas E. ;
Yi, Eunhee S. ;
Bauer, Philippe R. ;
Ryu, Jay H. .
RESPIRATORY MEDICINE, 2013, 107 (04) :616-621
[2]   Primary thymic extranodal marginal-zone B-Cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features [J].
Inagaki, H ;
Chan, JKC ;
Ng, JWM ;
Okabe, M ;
Yoshino, T ;
Okamoto, M ;
Ogawa, H ;
Matsushita, H ;
Yokose, T ;
Matsuno, Y ;
Nakamura, N ;
Nagasaka, T ;
Ueda, R ;
Eimoto, T ;
Nakamura, S .
AMERICAN JOURNAL OF PATHOLOGY, 2002, 160 (04) :1435-1443
[3]  
ISAACSON P, 1983, CANCER-AM CANCER SOC, V52, P1410, DOI 10.1002/1097-0142(19831015)52:8<1410::AID-CNCR2820520813>3.0.CO
[4]  
2-3
[5]   LOW-GRADE B-CELL LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID-TISSUE ARISING IN THE THYMUS - A THYMIC LYMPHOMA MIMICKING MYOEPITHELIAL SIALADENITIS [J].
ISAACSON, PG ;
CHAN, JKC ;
TANG, C ;
ADDIS, BJ .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1990, 14 (04) :342-351
[6]   Mucosa-associated lymphoid tissue lymphoma of the thymus associated with Sjogren's syndrome: Report of a case [J].
Kinoshita, Naoe ;
Ashizawa, Kazuto ;
Abe, Kuniko ;
Yamasaki, Naoya ;
Nakamura, Akihiro ;
Tagawa, Tsutomu ;
Soda, Hiroshi ;
Nagayasu, Takeshi ;
Hayashi, Tomayoshi .
SURGERY TODAY, 2008, 38 (05) :436-439
[7]   Thymic mucosa-associated lymphoid tissue lymphoma associated with bilateral orbital pseudotumor [J].
Kitai R. ;
Sasaki M. ;
Sato K. ;
Kubota T. ;
Takeuchi H. ;
Imamura Y. .
General Thoracic and Cardiovascular Surgery, 2009, 57 (10) :566-569
[8]   Mucosa-associated lymphoid tissue lymphoma in the thymus of a patient with systemic lupus erythematosus [J].
Maeda A. ;
Hayama M. ;
Nakata M. ;
Masaki H. ;
Tanemoto K. .
General Thoracic and Cardiovascular Surgery, 2008, 56 (6) :288-291
[9]   Pulmonary Mucosa-associated Lymphoid Tissue (MALT) Lymphoma with Multiple Thin-walled Pulmonary Cysts: A Case Report and Review of the Literature [J].
Noguchi, Shingo ;
Yatera, Kazuhiro ;
Kido, Takashi ;
Ogoshi, Takaaki ;
Nagata, Shuya ;
Nishida, Chinatsu ;
Yamasaki, Kei ;
Kawanami, Toshinori ;
Kawanami, Yukiko ;
Ishimoto, Hiroshi ;
Mukae, Hiroshi .
INTERNAL MEDICINE, 2013, 52 (20) :2325-2329
[10]   Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the thymus: Report of four cases [J].
Shimizu, K ;
Ishii, G ;
Nagai, K ;
Yokose, T ;
Ishizawa, K ;
Tamaru, J ;
Yoshida, J ;
Nishimura, M ;
Ochiai, A .
JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2005, 35 (07) :412-416