Backbone and sidechain 1H, 15N and 13C assignments of the NLRP7 pyrin domain

被引：3

作者：

Pinheiro, Anderson de Sa ^{[1
]}

Ehart, Angela ^{[2
]}

Ebner, Nina ^{[2
]}

Proell, Martina ^{[2
]}

Schwarzenbacher, Robert ^{[2
]}

Peti, Wolfgang ^{[1
]}

机构：

[1] Brown Univ, Dept Mol Pharmacol Physiol & Biotechnol, Providence, RI 02903 USA

[2] Salzburg Univ, Dept Mol Biol, A-5020 Salzburg, Austria

来源：

BIOMOLECULAR NMR ASSIGNMENTS | 2009年 / 3卷 / 02期

基金：

奥地利科学基金会;

关键词：

NLRP7; Pyrin; Innate immunity; Interleukin-1-beta; Inflammation; PROTEIN; FAMILY; EXPRESSION; REGULATOR; PYPAF3; NALP7;

D O I：

10.1007/s12104-009-9176-2

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The resonance assignments of the human NLRP7 PYD domain have been determined based on triple-resonance experiments using uniformly [C-13,N-15]-labeled protein. This assignment is the first step towards the 3D structure determination of the NLRP7 PYD domain.

引用

页码：207 / 209

页数：3

共 10 条

[1] The microbial and danger signals that activate Nod-like receptors [J].

Benko, Szilvia ;

Philpott, Dana J. ;

Girardin, Stephen E. .

CYTOKINE, 2008, 43 (03) :368-373

[2] NLRP7 mutations in women with diploid androgenetic and triploid moles: a proposed mechanism for mole formation [J].

Deveault, Catherine ;

Qian, Jian Hua ;

Chebaro, Wafaa ;

Ao, Asangla ;

Gilbert, Lucy ;

Mehio, Amira ;

Khan, Rabia ;

Tan, Seang Lin ;

Wischmeijer, Anita ;

Coullin, Philippe ;

Xie, Xing ;

Slim, Rima .

HUMAN MOLECULAR GENETICS, 2009, 18 (05) :888-897

[3] PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1β secretion [J].

Kinoshita, T ;

Wang, YT ;

Hasegawa, M ;

Imamura, R ;

Suda, T .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (23) :21720-21725

[4] Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1 [J].

Kinoshita, Takeshi ;

Kondoh, Chiaki ;

Hasegawa, Mizuho ;

Imamura, Ryu ;

Suda, Takashi .

INTERNATIONAL IMMUNOLOGY, 2006, 18 (12) :1701-1706

[5] Sensitivity of secondary structure propensities to sequence differences between α- and γ-synuclein:: Implications for fibrillation [J].

Marsh, Joseph A. ;

Singh, Vinay K. ;

Jia, Zongchao ;

Forman-Kay, Julie D. .

PROTEIN SCIENCE, 2006, 15 (12) :2795-2804

[6]

Ohno S, 2008, ANTICANCER RES, V28, P2493

[7] Oncogenic role of NALP7 in testicular seminomas [J].

Okada, K ;

Hirota, E ;

Mizutani, Y ;

Fujioka, T ;

Shuin, T ;

Miki, T ;

Nakamura, Y ;

Katagiri, T .

CANCER SCIENCE, 2004, 95 (12) :949-954

[8] The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences [J].

Proell, Martina ;

Riedl, Stefan J. ;

Fritz, Joerg H. ;

Rojas, Ana M. ;

Schwarzenbacher, Robert .

PLOS ONE, 2008, 3 (04)

[9] Overcoming expression and purification problems of RhoGDI using a family of "parallel" expression vectors [J].

Sheffield, P ;

Garrard, S ;

Derewenda, Z .

PROTEIN EXPRESSION AND PURIFICATION, 1999, 15 (01) :34-39

[10] NALPs: A novel protein family involved in inflammation [J].

Tschopp, J ;

Martinon, F ;

Burns, K .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2003, 4 (02) :95-104

← 1 →