Interpreting results of large-scale genetic association studies - Separating gold from fool's gold

被引：14
作者：
Dupuis, Josee
O'Donnell, Christopher J.
机构：
[1] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA USA
[2] NHLBI, Boston, MA USA
[3] NHLBI Framingham Heart Study, Boston, MA USA
[4] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Med,Cardiol Div, Boston, MA USA
来源：
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2007年 / 297卷 / 05期
关键词：
D O I：
10.1001/jama.297.5.529
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：529 / 531
页数：3
相关论文
共 17 条
[1]   A haplotype map of the human genome [J].
Altshuler, D ;
Brooks, LD ;
Chakravarti, A ;
Collins, FS ;
Daly, MJ ;
Donnelly, P ;
Gibbs, RA ;
Belmont, JW ;
Boudreau, A ;
Leal, SM ;
Hardenbol, P ;
Pasternak, S ;
Wheeler, DA ;
Willis, TD ;
Yu, FL ;
Yang, HM ;
Zeng, CQ ;
Gao, Y ;
Hu, HR ;
Hu, WT ;
Li, CH ;
Lin, W ;
Liu, SQ ;
Pan, H ;
Tang, XL ;
Wang, J ;
Wang, W ;
Yu, J ;
Zhang, B ;
Zhang, QR ;
Zhao, HB ;
Zhao, H ;
Zhou, J ;
Gabriel, SB ;
Barry, R ;
Blumenstiel, B ;
Camargo, A ;
Defelice, M ;
Faggart, M ;
Goyette, M ;
Gupta, S ;
Moore, J ;
Nguyen, H ;
Onofrio, RC ;
Parkin, M ;
Roy, J ;
Stahl, E ;
Winchester, E ;
Ziaugra, L ;
Shen, Y .
NATURE, 2005, 437 (7063) :1299-1320
[2]   A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization [J].
Arking, Dan E. ;
Pfeufer, Arne ;
Post, Wendy ;
Kao, W. H. Linda ;
Newton-Cheh, Christopher ;
Ikeda, Morna ;
West, Kristen ;
Kashuk, Carl ;
Akyol, Mahmut ;
Perz, Siegfried ;
Jalilzadeh, Shapour ;
Illig, Thomas ;
Gieger, Christian ;
Guo, Chao-Yu ;
Larson, Martin G. ;
Wichmann, H. Erich ;
Marban, Eduardo ;
O'Donnell, Christopher J. ;
Hirschhorn, Joel N. ;
Kaeaeb, Stefan ;
Spooner, Peter M. ;
Meitinger, Thomas ;
Chakravarti, Aravinda .
NATURE GENETICS, 2006, 38 (06) :644-651
[3]   CONTROLLING THE FALSE DISCOVERY RATE - A PRACTICAL AND POWERFUL APPROACH TO MULTIPLE TESTING [J].
BENJAMINI, Y ;
HOCHBERG, Y .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY, 1995, 57 (01) :289-300
[4]   Finishing the euchromatic sequence of the human genome [J].
Collins, FS ;
Lander, ES ;
Rogers, J ;
Waterston, RH .
NATURE, 2004, 431 (7011) :931-945
[5]   Statistical genetics - False discovery or missed discovery? [J].
Devlin, B ;
Roeder, K ;
Wasserman, L .
HEREDITY, 2003, 91 (06) :537-538
[6]   The structure of haplotype blocks in the human genome [J].
Gabriel, SB ;
Schaffner, SF ;
Nguyen, H ;
Moore, JM ;
Roy, J ;
Blumenstiel, B ;
Higgins, J ;
DeFelice, M ;
Lochner, A ;
Faggart, M ;
Liu-Cordero, SN ;
Rotimi, C ;
Adeyemo, A ;
Cooper, R ;
Ward, R ;
Lander, ES ;
Daly, MJ ;
Altshuler, D .
SCIENCE, 2002, 296 (5576) :2225-2229
[7]   A common genetic variant is associated with adult and childhood obesity [J].
Herbert, A ;
Gerry, NP ;
McQueen, MB ;
Heid, IM ;
Pfeufer, A ;
Illig, T ;
Wichmann, HE ;
Meitinger, T ;
Hunter, D ;
Hu, FB ;
Colditz, G ;
Hinney, A ;
Hebebrand, J ;
Koberwitz, K ;
Zhu, XF ;
Cooper, R ;
Ardlie, K ;
Lyon, H ;
Hirschhorn, JN ;
Laird, NM ;
Lenburg, ME ;
Lange, C ;
Christman, MF .
SCIENCE, 2006, 312 (5771) :279-283
[8]   A comprehensive review of genetic association studies [J].
Hirschhorn, JN ;
Lohmueller, K ;
Byrne, E ;
Hirschhorn, K .
GENETICS IN MEDICINE, 2002, 4 (02) :45-61
[9]   Genome-wide association studies for common diseases and complex traits [J].
Hirschhorn, JN ;
Daly, MJ .
NATURE REVIEWS GENETICS, 2005, 6 (02) :95-108
[10]   A road map for efficient and reliable human genome epidemiology [J].
Ioannidis, JPA ;
Gwinn, M ;
Little, J ;
Higgins, JPT ;
Bernstein, JL ;
Boffetta, P ;
Bondy, M ;
Bray, MS ;
Brenchley, PE ;
Buffler, PA ;
Casas, JP ;
Chokkalingam, A ;
Danesh, J ;
Smith, GD ;
Dolan, S ;
Duncan, R ;
Gruis, NA ;
Hartge, P ;
Hashibe, M ;
Hunter, DJ ;
Jarvelin, MR ;
Malmer, B ;
Maraganore, DM ;
Newton-Bishop, JA ;
O'Brien, TR ;
Petersen, G ;
Riboli, E ;
Salanti, G ;
Seminara, D ;
Smeeth, L ;
Taioli, E ;
Timpson, N ;
Uitterlinden, AG ;
Vineis, P ;
Wareham, N ;
Winn, DM ;
Zimmern, R ;
Khoury, MJ .
NATURE GENETICS, 2006, 38 (01) :3-5
12