Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study

被引:124
作者
Hawley, Samuel [1 ]
Javaid, M. Kassim [1 ,2 ]
Prieto-Alhambra, Daniel [1 ,2 ,3 ,4 ,5 ]
Lippett, Janet [6 ]
Sheard, Sally [1 ]
Arden, Nigel K. [1 ,2 ]
Cooper, Cyrus [1 ,2 ]
Judge, Andrew [1 ,2 ]
机构
[1] Univ Oxford, Oxford NIHR Musculoskeletal Biomed Res Unit, Oxford, England
[2] Univ Southampton, MRC, Lifecourse Epidemiol Unit, Southampton, Hants, England
[3] Univ Autonoma Barcelona, Hosp del Mar Med Res Inst IMIM, E-08193 Barcelona, Spain
[4] Inst Salud Carlos III, RETICEF, Barcelona, Spain
[5] Univ Autonoma Barcelona, IDIAP Jordi Gol Primary Care Res Inst, GREMPAL Res Grp, E-08193 Barcelona, Spain
[6] Royal Berkshire NHS Fdn Trust, Reading, Berks, England
基金
美国国家卫生研究院;
关键词
epidemiology; hip fracture; fracture liaison service; orthogeriatrician; osteoporosis; older people; OLDER PATIENTS; MORTALITY; MANAGEMENT; PREVENTION; GUIDELINE; OUTCOMES; WOMEN; RISK;
D O I
10.1093/ageing/afv204
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Setting: Hospital Episode Statistics database linked to Office for National Statistics mortality records for 11 acute hospitals in a region of England. Population: patients aged over 60 years admitted for a primary hip fracture from 2003 to 2013. Methods: each hospital was analysed separately and acted as its own control in a before-after time-series design in which the appointment of an orthogeriatrician or set-up/expansion of an FLS was evaluated. Multivariable Cox regression (mortality) and competing risk survival models (second hip fracture) were used. Fixed effects meta-analysis was used to pool estimates of impact for interventions of the same type. Results: of 33,152 primary hip fracture patients, 1,288 sustained a second hip fracture within 2 years (age and sex standardised proportion of 4.2%). 3,033 primary hip fracture patients died within 30 days and 9,662 died within 1 year (age and sex standardised proportion of 9.5% and 29.8%, respectively). The estimated impact of introducing an orthogeriatrician on 30-day and 1-year mortality was hazard ratio (HR) = 0.73 (95% CI: 0.65-0.82) and HR = 0.81 (CI: 0.75-0.87), respectively. Following an FLS, these associations were as follows: HR = 0.80 (95% CI: 0.71-0.91) and HR = 0.84 (0.77-0.93). There was no significant impact on time to second hip fracture. Conclusions: the introduction and/or expansion of orthogeriatric and FLS models of post-hip fracture care has a beneficial effect on subsequent mortality. No evidence for a reduction in second hip fracture rate was found.
引用
收藏
页码:236 / 242
页数:7
相关论文
共 30 条
[1]   Excess mortality following hip fracture: a systematic epidemiological review [J].
Abrahamsen, B. ;
van Staa, T. ;
Ariely, R. ;
Olson, M. ;
Cooper, C. .
OSTEOPOROSIS INTERNATIONAL, 2009, 20 (10) :1633-1650
[2]  
[Anonymous], 2007, The care of patients with fragility fracture
[3]   Incidence and risk factors for a second hip fracture in elderly women. The Study of Osteoporotic Fractures [J].
Chapurlat, RD ;
Bauer, DC ;
Nevitt, M ;
Stone, K ;
Cummings, SR .
OSTEOPOROSIS INTERNATIONAL, 2003, 14 (02) :130-136
[4]   New NICE guideline to improve outcomes for hip fracture patients [J].
Chesser, T. J. S. ;
Handley, R. ;
Swift, C. .
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2011, 42 (08) :727-729
[5]   Breaking the fragility fracture cycle [J].
Cooper, C. ;
Mitchell, P. ;
Kanis, J. A. .
OSTEOPOROSIS INTERNATIONAL, 2011, 22 (07) :2049-2050
[6]   Is Withholding Osteoporosis Medication After Fracture Sometimes Rational? A Comparison of the Risk for Second Fracture Versus Death [J].
Curtis, Jeffrey R. ;
Arora, Tarun ;
Matthews, Robert S. ;
Taylor, Allison ;
Becker, David J. ;
Colon-Emeric, Cathleen ;
Kilgore, Meredith L. ;
Morrisey, Michael A. ;
Saag, Kenneth G. ;
Safford, Monika M. ;
Warriner, Amy ;
Delzell, Elizabeth .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2010, 11 (08) :584-591
[7]   Osteoporosis Disease Management: The Role of the Orthopaedic Surgeon [J].
Dell, Richard ;
Greene, Denise ;
Schelkun, Steven R. ;
Williams, Kathy .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2008, 90A :188-194
[8]   Describing variation in the delivery of secondary fracture prevention after hip fracture: an overview of 11 hospitals within one regional area in England [J].
Drew, S. ;
Sheard, S. ;
Chana, J. ;
Cooper, C. ;
Javaid, M. K. ;
Judge, A. .
OSTEOPOROSIS INTERNATIONAL, 2014, 25 (10) :2427-2433
[9]   Models of care for the secondary prevention of osteoporotic fractures: a systematic review and meta-analysis [J].
Ganda, K. ;
Puech, M. ;
Chen, J. S. ;
Speerin, R. ;
Bleasel, J. ;
Center, J. R. ;
Eisman, J. A. ;
March, L. ;
Seibel, M. J. .
OSTEOPOROSIS INTERNATIONAL, 2013, 24 (02) :393-406
[10]   Fragility fractures and the osteoporosis care gap: An international phenomenon [J].
Giangregorio, L ;
Papaioannou, A ;
Cranney, A ;
Zytaruk, N ;
Adachi, JD .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2006, 35 (05) :293-305