Unusual Patterns of Neural Tube Defects in a High Risk Region of Northern China

被引：22

作者：

Chen, Gong ^{[1
]}

Pei, Li-Jun ^{[1
]}

Huang, Jian ^{[2
]}

Song, Xin-Ming ^{[1
]}

Lin, Liang-Mug ^{[1
]}

Gu, Xue ^{[3
]}

Wu, Jian-Xin ^{[3
]}

Wang, Fang ^{[3
]}

Wu, Ji-Lei ^{[3
]}

Chen, Jia-Peng ^{[1
]}

Liu, Ju-Fen ^{[1
]}

Xin, Ruo-Lei ^{[3
]}

Zhang, Ting ^{[3
]}

Zheng, Xiao-Ying ^{[1
]}

机构：

[1] Peking Univ, Inst Populat Res, Beijing 100871, Peoples R China

[2] Chinese Ctr Dis Control & Prevent, Inst Nutr & Food Safety, Beijing 100050, Peoples R China

[3] Capital Inst Pediat, Beijing 100020, Peoples R China

来源：

BIOMEDICAL AND ENVIRONMENTAL SCIENCES | 2009年 / 22卷 / 04期

关键词：

Neural tube defects; Epidemiology; Geographic variation; CONGENITAL-MALFORMATIONS; ETIOLOGIC HETEROGENEITY; PREVALENCE; AREA; BIRTH; INDIA;

D O I：

10.1016/S0895-3988(09)60065-9

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Objective To study the prevalence of different types of neural tube defects (NTDs) in Luliang Prefecture, Shanxi province, where the prevalence of NTDs is unusually high and the correlation between NTDs prevalence and patterns. Methods A surveillance population-based birth defects was performed in Luliang Prefecture, Shanxi province. Results The results of our study showed that the prevalence of NTDs was 2-fold higher in Luliang Prefecture than in other areas of Shanxi province. Unusual patterns of NTDs were found, however, multiple NTDs were relatively common in Luliang Prefecture, accounting for over 13% of all NTDs cases in China. Conclusion The prevalence of NTDs is associated with its patterns.

引用

页码：340 / 344

页数：5

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