Rolling on N-linked glycans:: a new way to present L-selectin binding sites

被引:11
作者
Alon, Ronen [1 ]
Rosen, Steven
机构
[1] Weizmann Inst Sci, Dept Immunol, IL-76100 Rehovot, Israel
[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Program Immunol, San Francisco, CA 94143 USA
关键词
D O I
10.1038/ni0407-339
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recruitment of lymphocytes to the lymph nodes requires L-selectin-mediated recognition of carbohydrate determinants presented by O-glycans. New work shows that N-glycans 'decorated' with the same determinants also contribute to lymphocyte homing.
引用
收藏
页码:339 / 341
页数:4
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