Multisystem inflammatory syndrome in children associated with SARS-CoV-2 in a solid organ transplant recipient

被引:10
作者
Petters, Leanne M. [1 ,2 ]
Vogel, Tiphanie P. [2 ,3 ]
Munoz, Flor M. [1 ,2 ]
Hernandez, Jose A. [2 ,4 ]
Koohmaraie, Sarah [2 ]
Nowicki, Michael J. [5 ]
Zumbro, Caleb E. [5 ,6 ]
Mysore, Krupa R. [2 ,7 ]
机构
[1] Baylor Coll Med, Dept Pediat, Sect Infect Dis, Houston, TX 77030 USA
[2] Texas Childrens Hosp, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Pediat, Sect Rheumatol, Houston, TX 77030 USA
[4] Baylor Coll Med, Dept Radiol, Sect Pediat Intervent Radiol, Houston, TX 77030 USA
[5] Univ Mississippi, Med Ctr, Dept Pediat, Jackson, MS 39216 USA
[6] Univ Mississippi, Med Ctr, Dept Med, Jackson, MS 39216 USA
[7] Baylor Coll Med, Dept Pediat, Sect Gastroenterol Hepatol & Nutr, Houston, TX 77030 USA
关键词
clinical research; practice; complication; infection and infectious agents ‐ viral; infectious disease; liver transplantation; hepatology; pediatrics; COVID-19;
D O I
10.1111/ajt.16572
中图分类号
R61 [外科手术学];
学科分类号
摘要
We present the case of a 3-year-old female liver transplant recipient with a history of Caroli disease who presented with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) test and was ultimately diagnosed with multisystem inflammatory syndrome in children (MIS-C) complicated by portal vein thrombosis. To the best of our knowledge, this is the first case report of MIS-C in a pediatric solid organ transplant (SOT) recipient. Based on our patient, MIS-C could be a potential complication of Coronavirus disease 2019 (COVID-19) in SOT recipients and may have a negative outcome on transplant graft function.
引用
收藏
页码:2596 / 2599
页数:4
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