A novel fluorescent probe based on the flexible dipicolylamine: Recognizing zinc(II) in aqueous solution and imaging in living cell

被引：19

作者：

Zhang, Na ^{[1
]}

Tian, Xiaohe ^{[1
]}

Zheng, Jun ^{[3
]}

Zhang, Xiuzhen ^{[3
]}

Zhu, Weiju ^{[1
]}

Tian, Yupeng ^{[1
]}

Zhu, Qiyong ^{[2
]}

Zhou, Hongping ^{[1
]}

机构：

[1] Anhui Univ, Key Lab Funct Inorgan Mat Chem Anhui Prov, Coll Chem & Chem Engn, Hefei 230601, Peoples R China

[2] Huainan Normal Coll, Dept Chem, Huainan 232001, Peoples R China

[3] Anhui Univ, Ctr Modern Expt Technol, Hefei 230039, Peoples R China

来源：

DYES AND PIGMENTS | 2016年 / 124卷

基金：

中国国家自然科学基金;

关键词：

DPA; Probe; Recognition abilities; Zinc ion; Fluorescence spectra; Cell imaging; SIMPLE PYRAZOLINE; ON PROBE; ZN2+; SENSOR; RECOGNITION; CHEMOSENSOR; SELECTIVITY; EMISSION;

D O I：

10.1016/j.dyepig.2015.09.019

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel fluorescent probe for Zn2+ has been designed and synthesized based on a dipicolylamine group connected by a benzimidazole amide backbone. A comprehensive analysis of the recognition ability of the probe towards metal ions was conducted by ultraviolet absorption and fluorescence emission spectroscopy. Results demonstrated that the probe showed selective and sensitive fluorescence turn-on signaling behavior toward Zn2+ in HEPES buffered (pH = 7.4) aqueous solution. The detection limit of this probe was calculated to be 5.10 x 10(-8) M for Zn2+. Fluorescent imaging inside HepG2 cells indicated potential application of the probe for detecting Zn2+ ions in living cell imaging. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：174 / 179

页数：6

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