Pediatric intradural extramedullary synovial sarcoma: Case report

被引：14

作者：

Greene, Stephanie ^{[1
]}

Hawkins, Douglas S.

Rutledge, Joe C.

Tsuchiya, Karen D.

Douglas, James

Ellenbogen, Richard G.

Avellino, Anthony M.

机构：

[1] Univ Washington, Childrens Hosp & Reg Med Ctr, Sch Med, Dept Neurol Surg, Seattle, WA 98195 USA

[2] Univ Washington, Childrens Hosp & Reg Med Ctr, Sch Med, Dept Pediat,Div Hematol & Oncol, Seattle, WA 98195 USA

[3] Univ Washington, Childrens Hosp & Reg Med Ctr, Sch Med, Dept Lab Med, Seattle, WA 98195 USA

[4] Univ Washington, Childrens Hosp & Reg Med Ctr, Sch Med, Dept Radiat Oncol, Seattle, WA 98195 USA

来源：

NEUROSURGERY | 2006年 / 59卷 / 06期

关键词：

extramedullary; intradural; pediatric; sarcoma; spinal; synovial;

D O I：

10.1227/01.NEU.0000245619.24603.96

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

OBJECTIVE: The diagnosis of intradural synovial sarcoma has not been previously published. This report provides a summary of the literature on this tumor and on tumors arising in this location, as well as a description of this patient's clinical course. CLINICAL PRESENTATION: An 11-year-old girl presented with back pain and radiculopathy. A magnetic resonance imaging scan of the spine revealed a spinal intradural, extramedullary mass at L2-L4 and four additional nodules of enhancement. INTERVENTION: The mass was nearly totally resected. Radiation and chemotherapy were administered. Intracranial metastases became evident during treatment. The patient died of the disease 14 months after diagnosis. CONCLUSION: The rapid progression of leptomeningeal metastasis despite maximal treatment demonstrates the aggressive nature of the tumor and the need for further study. Copyright © by the Congress of Neurological Surgeons.

引用

页码：1339 / 1339

页数：1

共 45 条

[1]

Acharya R., Bhalla S., Seghal A.D., Malignant peripheral nerve sheath tumor of the cauda equina, Neurol Sci, 22, pp. 267-270, (2001)

[2]

Barbagallo G.M., Lanzafame S., Nicol G.F., Platania N., Albanese V., Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: A spinal gliosarcoma? Case report and review of the literature, J Neurosurg, 96, SUPPL. 2, pp. 230-235, (2002)

[3]

Bilsky M.H., Boland P.J., Panageas K.S., Woodruff J.M., Brennan M.F., Healey J.H., Intralesional resection of primary and metastatic sarcoma involving the spine: Outcome analysis of 59 patients, Neurosurgery, 49, pp. 1277-1287, (2001)

[4]

Bosma J.J., Kirollos R.W., Broome J., Eldridge P.R., Primary intradural classic chondrosarcoma: Case report and literature review, Neurosurgery, 48, pp. 420-423, (2001)

[5]

De Silva M.V., McMahon A.D., Reid R., Prognostic factors associated with local recurrence, metastases, and tumor-related death in patients with synovial sarcoma, Am J Clin Oncol, 27, pp. 113-121, (2004)

[6]

Chu P.G., Benhattar J., Weiss L.M., Meagher-Villemure K., Intraneural synovial sarcoma: Two cases, Mod Pathol, 17, pp. 258-263, (2004)

[7]

Deshmukh R., Mankin H.J., Singer S., Synovial sarcoma: The importance of size and location for survival, Clin Orthop Relat Res, 419, pp. 155-161, (2004)

[8]

DeSousa A.L., Kalsbeck J.E., Mealey Jr. J., Campbell R.L., Hockey A., Intraspinal tumors in children: A review of 81 cases, J Neurosurg, 51, pp. 437-445, (1979)

[9]

Ferrari A., Gronchi A., Casanova M., Meazza C., Gandola L., Collini P., Lozza L., Bertulli R., Olmi P., Casali P.G., Synovial sarcoma: A retrospective analysis of 271 patients of all ages treated at a single institution, Cancer, 101, pp. 627-634, (2004)

[10]

Guillou L., Coindre J., Gallagher G., Terrier P., Gebhard S., De Saint Aubain Somerhausen N., Michels J., Jundt G., Vince D.R., Collin F., Trassard M., Le Doussal V., Benhattar J., Detection of the synovial sarcoma translocation t(X

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