Diabetes Management in Patients with Heart Failure

被引:11
作者
Shen, Jia [1 ]
Greenberg, Barry H. [1 ]
机构
[1] Univ Calif San Diego, Dept Med, Div Cardiol, La Jolla, CA 92093 USA
关键词
Diabetes mellitus; Heart failure; Risk factors; Sodium glucose cotransporter 2 inhibitor; COTRANSPORTER; 2; INHIBITORS; REDUCED EJECTION FRACTION; CARDIOVASCULAR OUTCOMES; SGLT2; CLINICAL-OUTCOMES; RECEPTOR AGONISTS; GLYCEMIC CONTROL; EMPA-REG; TYPE-2; RISK;
D O I
10.4093/dmj.2020.0296
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetes and heart failure (HF) are common diseases, each affecting large segments of the world population. Moreover, prevalence rates for both are expected to rise dramatically over coming decades. The high prevalence rates of both diseases and well-recognized association of diabetes as a risk factor for HF make it inevitable that both diseases co-exist in a large number of patients, complicating their management and increasing the risk of a poor outcome. Management of diabetes has been shown to impact clinical events in patients with HF and there is emerging evidence that agents used to treat diabetes can reduce HF events, even in non-diabetic patients. In this review we summarize the clinical course and treatment of patients with type 2 diabetes mellitus (T2DM) and HF and review the efficacy and safety of pharmacological agents in patients with T2DM at risk for HF and those with established disease.
引用
收藏
页码:158 / 172
页数:15
相关论文
共 99 条
[91]   Updating insights into rosiglitazone and cardiovascular risk through shared data: individual patient and summary level meta-analyses [J].
Wallach, Joshua D. ;
Wang, Kun ;
Zhang, Audrey D. ;
Cheng, Deanna ;
Nardini, Holly K. Grossetta ;
Lin, Haiqun ;
Bracken, Michael B. ;
Desai, Mayur ;
Krumholz, Harlan M. ;
Ross, Joseph S. .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 368
[92]   Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes [J].
White, William B. ;
Cannon, Christopher P. ;
Heller, Simon R. ;
Nissen, Steven E. ;
Bergenstal, Richard M. ;
Bakris, George L. ;
Perez, Alfonso T. ;
Fleck, Penny R. ;
Mehta, Cyrus R. ;
Kupfer, Stuart ;
Wilson, Craig ;
Cushman, William C. ;
Zannad, Faiez ;
Aiub, Jorge ;
Albisu, Juan ;
Alvarez, Carlos ;
Astesiano, Alfredo ;
Barcudi, Raul ;
Bendersky, Mario ;
Bono, Julio ;
Bustos, Betina ;
Cartasegna, Luis ;
Caruso, Orlando ;
Casabe, Horacio ;
Castro, Remo ;
Colombo, Hugo ;
Cuneo, Carlos ;
Cura, Fernando ;
De Loredo, Luis ;
Dran, Ricardo ;
Fernandez, Horacio ;
Garcia Pinna, Jorge ;
Hrabar, Adrian ;
Klyver de Saleme, Maria ;
Luquez, Hugo ;
Mackinnon, Ignacio ;
Maffei, Laura ;
Majul, Claudio ;
Mallagray, Marcelo ;
Marino, Javier ;
Martinez, Diego ;
Martingano, Roberto ;
Nul, Daniel ;
Leonor Parody, Maria ;
Petrucci, Jacqueline ;
Pieroni, Mario ;
Piskorz, Daniel ;
Prado, Aldo ;
Ramos, Hugo ;
Resk, Jorge .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (14) :1327-1335
[93]   Impact of DPP-4 inhibition on acute and chronic endothelial function in humans with type 2 diabetes on background metformin therapy [J].
Widlansky, Michael E. ;
Puppala, Venkata K. ;
Suboc, Tisha M. ;
Malik, Mobin ;
Branum, Amberly ;
Signorelli, Kara ;
Wang, Jingli ;
Ying, Rong ;
Tanner, Michael J. ;
Tyagi, Sudhi .
VASCULAR MEDICINE, 2017, 22 (03) :189-196
[94]  
Wiviott SD, 2019, NEW ENGL J MED, V380, P347, DOI [10.1056/NEJMc1902837, 10.1056/NEJMoa1812389]
[96]   SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials [J].
Zannad, Faiez ;
Ferreira, Joao Pedro ;
Pocock, Stuart J. ;
Anker, Stefan D. ;
Butler, Javed ;
Filippatos, Gerasimos ;
Brueckmann, Martina ;
Ofstad, Anne Pernille ;
Pfarr, Egon ;
Jamal, Waheed ;
Packer, Milton .
LANCET, 2020, 396 (10254) :819-829
[97]   Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms. [J].
Zannad, Faiez ;
McMurray, John J. V. ;
Krum, Henry ;
van Veldhuisen, Dirk J. ;
Swedberg, Karl ;
Shi, Harry ;
Vincent, John ;
Pocock, Stuart J. ;
Pitt, Bertram .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (01) :11-21
[98]   SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials [J].
Zelniker, Thomas A. ;
Wiviott, Stephen D. ;
Raz, Itamar ;
Im, Kyungah ;
Goodrich, Erica L. ;
Bonaca, Marc P. ;
Mosenzon, Ofri ;
Kato, Eri T. ;
Cahn, Avivit ;
Furtado, Remo H. M. ;
Bhatt, Deepak L. ;
Leiter, Lawrence A. ;
McGuire, Darren K. ;
Wilding, John P. H. ;
Sabatine, Marc S. .
LANCET, 2019, 393 (10166) :31-39
[99]   Association Between Use of Sodium-Glucose Cotransporter 2 Inhibitors, Glucagon-like Peptide 1 Agonists, and Dipeptidyl Peptidase 4 Inhibitors With All-Cause Mortality in Patients With Type 2 Diabetes A Systematic Review and Meta-analysis [J].
Zheng, Sean L. ;
Roddick, Alistair J. ;
Aghar-Jaffar, Rochan ;
Shun-Shin, Matthew J. ;
Francis, Darrel ;
Oliver, Nick ;
Meeran, Karim .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 319 (15) :1580-1591