Cardiac Amyloidosis Therapy: A Systematic Review

被引：0

作者：

Iodice, Franco ^{[1
]}

Di Mauro, Marco ^{[1
]}

Migliaccio, Marco Giuseppe ^{[1
]}

Iannuzzi, Angela ^{[1
]}

Pacileo, Roberta ^{[1
]}

Caiazza, Martina ^{[1
]}

Esposito, Augusto ^{[1
]}

机构：

[1] Univ Campania Luigi Vanvitelli, Dept Translat Med Sci, I-81100 Naples, Italy

来源：

CARDIOGENETICS | 2021年 / 11卷 / 01期

关键词：

cardiac amyloidosis; therapies amyloidosis; CHAIN AL AMYLOIDOSIS; LIGHT-CHAIN; P COMPONENT; PHARMACOLOGICAL DEPLETION; LIVER-TRANSPLANTATION; NATURAL-HISTORY; BENDAMUSTINE; IMPLANTATION; STABILIZER; DIAGNOSIS;

D O I：

10.3390/cardiogenetics11010002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart involvement in Cardiac Amyloidosis (CA) results in a worsening of the prognosis in almost all patients with both light-chain (AL) and transthyretin amyloidosis (ATTR). The mainstream CA is a restrictive cardiomyopathy with hypertrophic phenotype at cardiac imaging that clinically leads to heart failure with preserved ejection fraction (HFpEF). An early diagnosis is essential to reduce cardiac damage and to improve the prognosis. Many therapies are available, but most of them have late benefits to cardiac function; for this reason, novel therapies are going to come soon.

引用

页码：10 / 17

页数：8

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