Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder

被引：68

作者：

Van Boven, Robert W. ^{[1
]}

Harrington, Greg S. ^{[1
]}

Hackney, David B. ^{[2
]}

Ebel, Andreas ^{[3
]}

Gauger, Grant

Bremner, J. Douglas ^{[4
]}

D'Esposito, Mark ^{[5
]}

Detre, John A. ^{[6
]}

Haacke, E. Mark ^{[7
]}

Jack, Clifford R., Jr. ^{[8
]}

Jagust, William J.

Le Bihan, Denis ^{[9
]}

Mathis, Chester A. ^{[10
]}

Mueller, Susanne ^{[3
]}

Mukherjee, Pratik

Schuff, Norbert ^{[3
]}

Chen, Anthony ^{[11
]}

Weiner, Michael W. ^{[3
]}

机构：

[1] Cent Texas Dept Vet Affairs VA Hlth Care Syst, Brain Imaging & Recovery Lab, Austin, TX USA

[2] Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Radiol, Boston, MA 02215 USA

[3] Univ Calif San Francisco, Ctr Imaging Neurodegenerat Dis, VA Med Ctr, San Francisco, CA 94143 USA

[4] Emory Univ, Sch Med, Emory Clin Neurosci Res Unit, Atlanta VA Med Ctr, Atlanta, GA USA

[5] Univ Calif Berkeley, Helen Wills Neurosci Inst, Henry H Wheeler Jr Brain Imaging Ctr, Berkeley, CA 94720 USA

[6] Univ Penn, Dept Neurol & Radiol, Ctr Funct Neuroimaging, Philadelphia, PA 19104 USA

[7] Wayne State Univ, Magnet Resonance Imaging Inst Biomed Res, Detroit, MI USA

[8] Mayo Clin, Rochester, MN USA

[9] CEA Saclay, F-91191 Gif Sur Yvette, France

[10] Univ Pittsburgh, PET Facil, Pittsburgh, PA USA

[11] San Francisco VA Med Ctr, Program Rehabil Neurosci, San Francisco, CA USA

来源：

JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT | 2009年 / 46卷 / 06期

关键词：

diagnosis; diffusion tensor imaging; fMRI; neuroimaging; OIF/OEF; posttraumatic stress disorder; PTSD; TBI; traumatic brain injury; veterans; MAGNETIC-RESONANCE-SPECTROSCOPY; CEREBRAL-BLOOD-FLOW; DIFFUSE AXONAL INJURY; SMALLER HIPPOCAMPAL VOLUME; CONTROLLED CORTICAL IMPACT; CHILDHOOD SEXUAL-ABUSE; POSITRON-EMISSION-TOMOGRAPHY; MEDIAL PREFRONTAL CORTEX; PROTON MR SPECTROSCOPY; APPEARING WHITE-MATTER;

D O I：

10.1682/JRRD.2008.12.0161

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

Improved diagnosis and treatment of traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) are needed for our military and veterans, their families, and society at large. Advances in brain imaging offer important biomarkers of structural, functional, and metabolic information concerning the brain. This article reviews the application of various imaging techniques to the clinical problems of TBI and PTSD. For TBI, we focus on findings and advances in neuroimaging that hold promise for better detection, characterization, and monitoring of objective brain changes in symptomatic patients with combat-related, closed-head brain injuries not readily apparent by standard computed tomography or conventional magnetic resonance imaging techniques.

引用

页码：717 / 755

页数：39

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