Trace element status (Se, Cu, Zn) and serum lipid profile in Portuguese subjects of San Miguel Island from Azores' archipelago

被引:32
作者
Viegas-Crespo, AM [1 ]
Pavao, ML
Paulo, O
Santos, V
Santos, MC
Nève, J
机构
[1] Univ Lisbon, Fac Sci, Dept Zool, CBA, P-1749016 Lisbon, Portugal
[2] Univ Azores, Dept Technol Sci & Dev, P-9500 Ponta Delgada, Portugal
[3] Hosp Ponta Delgada, P-9500 Ponta Delgada, Portugal
[4] Univ Lisbon, Fac Sci, Dept Chem & Biochem, Inst Sci Res Bento da Rocha Cabral,CEBF, P-1749016 Lisbon, Portugal
[5] Free Univ Brussels, Inst Pharm, B-1050 Brussels, Belgium
关键词
trace elements; selenium; copper; zinc; lipid profile; Azores;
D O I
10.1016/S0946-672X(00)80016-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Data on selenium, copper and zinc in serum of Portuguese inhabitants of the city of Ponta Delgada - Azores Archipelago are reported for the first time. The subjects are of both sexes, aged 20 to 60 years, and non-abusers of alcohol, tobacco or drugs. Serum concentrations of these elements are in the same range than those found for populations of Lisbon and of some other European countries. Differences between sexes are observed, with serum selenium and zinc levels being higher in males than in females, and the copper levels being higher in females as compared to males. These results can be explained by the hormonal status and/or oral contraceptive steroids intake, particularly for copper Concerning lipid profile, the majority of individuals have serum lipid parameters within the normal range. In addition, no difference in trace element levels between normo and hyperlipidemic individuals is observed and no conclusive results about the relationship of all evaluated parameters to alcohol, tobacco and drug consumption are observed, in agreement with data obtained in the population of Lisbon.
引用
收藏
页码:1 / 5
页数:5
相关论文
共 25 条
[1]  
Flohe L., 1989, GLUTATHIONE CHEM BIO, P643
[2]  
GIDEZ LI, 1982, J LIPID RES, V23, P1206
[3]  
Harman D, 1992, EXS, V62, P1
[4]   REGULATION OF ANTIOXIDANT ENZYMES [J].
HARRIS, ED .
FASEB JOURNAL, 1992, 6 (09) :2675-2683
[5]   Thioredoxin reductase activity is decreased by selenium deficiency [J].
Hill, KE ;
McCollum, GW ;
Boeglin, ME ;
Burk, RF .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 234 (02) :293-295
[6]  
LUOMA PV, 1984, RES COMMUN CHEM PATH, V46, P469
[7]   EFFECT OF ZINC ON THE PROLIFERATIVE RESPONSE OF HUMAN-LYMPHOCYTES - MECHANISM OF ITS MITOGENIC ACTION [J].
MALAVE, I ;
RODRIGUEZ, J ;
ARAUJO, Z ;
ROJAS, I .
IMMUNOPHARMACOLOGY, 1990, 20 (01) :1-10
[8]   Role of glutathione peroxidase and phospholipid hydroperoxide glutathione peroxidase in the reduction of lysophospholipid hydroperoxides [J].
Marinho, HS ;
Antunes, F ;
Pinto, RE .
FREE RADICAL BIOLOGY AND MEDICINE, 1997, 22 (05) :871-883
[9]  
Neve J, 1996, J Cardiovasc Risk, V3, P42
[10]   ERYTHROCYTE AND PLASMA TRACE-ELEMENT LEVELS IN CLINICAL ASSESSMENTS - ZINC, COPPER, AND SELENIUM IN NORMALS AND PATIENTS WITH DOWNS-SYNDROME AND CYSTIC-FIBROSIS [J].
NEVE, J ;
MOLLE, L ;
HANOCQ, M ;
SINET, PM ;
VANGEFFEL, R .
BIOLOGICAL TRACE ELEMENT RESEARCH, 1983, 5 (02) :75-79