A new consecutive three-component oxazole synthesis by an amidation-coupling-cycloisomerization (ACCI) sequence

被引：106
作者：
Merkul, Eugen [1 ]
Mueller, Thomas J. J. [1 ]
机构：
[1] Univ Heidelberg, Inst Organ Chem, D-69120 Heidelberg, Germany
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 46期
关键词：
D O I：
10.1039/b610839c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel consecutive three-component synthesis of 1-(hetero)aryl- 2-(2-(hetero)aryl-oxazol-5-yl) ethanones starting from propargyl amine and acid chlorides, both for amidation and cross-coupling, is based upon an amidation-coupling-cycloisomerization (ACCI) sequence.
引用
收藏
页码：4817 / 4819
页数：3
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