Interleukin-6 Receptor Inhibition in Covid-19-Cooling the Inflammatory Soup

被引：104

作者：

Rubin, Eric J.

Longo, Dan L.

Baden, Lindsey R.

机构：

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 384卷 / 16期

关键词：

PNEUMOCYSTIS-CARINII PNEUMONIA; CORTICOSTEROIDS; TOCILIZUMAB;

D O I：

10.1056/NEJMe2103108

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1564 / 1565

页数：2

共 11 条

[1] A CONTROLLED TRIAL OF EARLY ADJUNCTIVE TREATMENT WITH CORTICOSTEROIDS FOR PNEUMOCYSTIS-CARINII PNEUMONIA IN THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].

BOZZETTE, SA ;

SATTLER, FR ;

CHIU, J ;

WU, AW ;

GLUCKSTEIN, D ;

KEMPER, C ;

BARTOK, A ;

NIOSI, J ;

ABRAMSON, I ;

COFFMAN, J ;

HUGHLETT, C ;

LOYA, R ;

CASSENS, B ;

AKIL, B ;

MENG, TC ;

BOYLEN, CT ;

NIELSEN, D ;

RICHMAN, DD ;

TILLES, JG ;

LEEDOM, J ;

MCCUTCHAN, JA .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (21) :1451-1457

[2] CORTICOSTEROIDS AS ADJUNCTIVE THERAPY FOR SEVERE PNEUMOCYSTIS-CARINII PNEUMONIA IN THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

GAGNON, S ;

BOOTA, AM ;

FISCHL, MA ;

BAIER, H ;

KIRKSEY, OW ;

LAVOIE, L .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (21) :1444-1450

[3]

Gordon AC, 2021, NEW ENGL J MED, V384, P1491, DOI [10.1056/NEJMc2108482, 10.1056/NEJMoa2100433]

[4] Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia A Randomized Clinical Trial [J].

Hermine, Olivier ;

Mariette, Xavier ;

Tharaux, Pierre-Louis ;

Resche-Rigon, Matthieu ;

Porcher, Raphael ;

Ravaud, Philippe .

JAMA INTERNAL MEDICINE, 2021, 181 (01) :32-40

[5]

Horby P, 2021, NEW ENGL J MED, V384, P693, DOI [10.1056/NEJMoa2021436, 10.1056/NEJMoa2022926]

[6]

Horby PW, 2021, LANCET, V397, P1637, DOI 10.1016/S0140-6736(21)00676-0

[7] Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia [J].

Rosas, I. O. ;

Brau, N. ;

Waters, M. ;

Go, R. C. ;

Hunter, B. D. ;

Bhagani, S. ;

Skiest, D. ;

Aziz, M. S. ;

Cooper, N. ;

Douglas, I. S. ;

Savic, S. ;

Youngstein, T. ;

Del Sorbo, L. ;

Gracian, A. Cubillo ;

De la Zerda, D. J. ;

Ustianowski, A. ;

Bao, M. ;

Dimonaco, S. ;

Graham, E. ;

Matharu, B. ;

Spotswood, H. ;

Tsai, L. ;

Malhotra, A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (16) :1503-1516

[8] Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia [J].

Salama, Carlos ;

Han, Jian ;

Yau, Linda ;

Reiss, William G. ;

Kramer, Benjamin ;

Neidhart, Jeffrey D. ;

Criner, Gerard J. ;

Kaplan-Lewis, Emma ;

Baden, Rachel ;

Pandit, Lavannya ;

Cameron, Miriam L. ;

Garcia-Diaz, Julia ;

Chavez, Victoria ;

Mekebeb-Reuter, Martha ;

de Menezes, Ferdinando Lima ;

Shah, Reena ;

Gonzalez-Lara, Maria F. ;

Assman, Beverly ;

Freedman, Jamie ;

Mohan, Shalini, V .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (01) :20-30

[9] Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia A Randomized Clinical Trial [J].

Salvarani, Carlo ;

Dolci, Giovanni ;

Massari, Marco ;

Merlo, Domenico Franco ;

Cavuto, Silvio ;

Savoldi, Luisa ;

Bruzzi, Paolo ;

Boni, Fabrizio ;

Braglia, Luca ;

Turra, Caterina ;

Ballerini, Pier Ferruccio ;

Sciascia, Roberto ;

Zammarchi, Lorenzo ;

Para, Ombretta ;

Scotton, Pier Giorgio ;

Inojosa, Walter Omar ;

Ravagnani, Viviana ;

Salerno, Nicola Duccio ;

Sainaghi, Pier Paolo ;

Brignone, Alessandro ;

Codeluppi, Mauro ;

Teopompi, Elisabetta ;

Milesi, Maurizio ;

Bertomoro, Perla ;

Claudio, Norbiato ;

Salio, Mario ;

Falcone, Marco ;

Cenderello, Giovanni ;

Donghi, Lorenzo ;

Del Bono, Valerio ;

Colombelli, Paolo Luigi ;

Angheben, Andrea ;

Passaro, Angelina ;

Secondo, Giovanni ;

Pascale, Renato ;

Piazza, Ilaria ;

Facciolongo, Nicola ;

Costantini, Massimo .

JAMA INTERNAL MEDICINE, 2021, 181 (01) :24-31

[10] Efficacy of Tocilizumab in Patients Hospitalized with Covid-19 [J].

Stone, John H. ;

Frigault, Matthew J. ;

Serling-Boyd, Naomi J. ;

Fernandes, Ana D. ;

Harvey, Liam ;

Foulkes, Andrea S. ;

Horick, Nora K. ;

Healy, Brian C. ;

Shah, Ruta ;

Bensaci, Ana Maria ;

Woolley, Ann E. ;

Nikiforow, Sarah ;

Lin, Nina ;

Sagar, Manish ;

Schrager, Harry ;

Huckins, David S. ;

Axelrod, Matthew ;

Pincus, Michael D. ;

Fleisher, Jorge ;

Sacks, Chana A. ;

Dougan, Michael ;

North, Crystal M. ;

Halvorsen, Yuan-Di ;

Thurber, Tara K. ;

Dagher, Zeina ;

Scherer, Allison ;

Wallwork, Rachel S. ;

Kim, Arthur Y. ;

Schoenfeld, Sara ;

Sen, Pritha ;

Neilan, Tomas G. ;

Perugino, Cory A. ;

Unizony, Sebastian H. ;

Collier, Deborah S. ;

Matza, Mark A. ;

Yinh, Janeth M. ;

Bowman, Kathryn A. ;

Meyerowitz, Eric ;

Zafar, Amna ;

Drobni, Zsofia D. ;

Bolster, Marcy B. ;

Kohler, Minna ;

D'Silva, Kristin M. ;

Dau, Jonathan ;

Lockwood, Megan M. ;

Cubbison, Caroline ;

Weber, Brittany N. ;

Mansour, Michael K. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (24) :2333-2344

← 1 2 →