Alternative Mechanisms for Tn5 Transposition

被引：5
|
作者：
Ahmed, Asad [1 ]
机构：
[1] Univ Alberta, Dept Biol Sci, Edmonton, AB, Canada
来源：
PLOS GENETICS | 2009年 / 5卷 / 08期
关键词：
SITE-SPECIFIC RECOMBINATION; BACTERIOPHAGE-MU; DNA; SYSTEM; TN10; INTERMEDIATE; DELETIONS; ELEMENTS; MODEL;
D O I：
10.1371/journal.pgen.1000619
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Bacterial transposons are known to move to new genomic sites using either a replicative or a conservative mechanism. The behavior of transposon Tn5 is anomalous. In vitro studies indicate that it uses a conservative mechanism while in vivo results point to a replicative mechanism. To explain this anomaly, a model is presented in which the two mechanisms are not independent-as widely believed-but could represent alternate outcomes of a common transpositional pathway.
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页数：5
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