A case of antisynthetase syndrome with chilblains-like lesions and microangiopathy

被引：3

作者：

Abrassart, Tom ^{[1
]}

Roland, Thomas ^{[1
]}

Laurent, France ^{[1
]}

Rossi, Camelia ^{[1
]}

机构：

[1] Ctr Hosp Univ Ambroise Pare, Dept Internal Med & Infect Dis, Mons, Belgium

来源：

CLINICAL CASE REPORTS | 2021年 / 9卷 / 03期

关键词：

acrosyndrome; antisynthetase syndrome; microangiopathy; myalgia;

D O I：

10.1002/ccr3.3790

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present the case of a 50-year-old woman with febrile myalgia, chilblains-like lesions, and cough. Antinuclear antibodies and anti-PL-12 antisynthetase autoantibodies were found in complementary examinations. Interstitial lung disease was found on chest computed tomography. Nailfold capillaroscopy showed microangiopathic lesions. Antisynthetase syndrome is a recently described entity in inflammatory myopathies, with specific clinical criteria. Interstitial lung disease is very common, especially in anti-PL-12 associated antisynthetase syndrome. Raynaud`s phenomenon is another well-defined criterion. However, microangiopathic damage is probably underestimated and the role of nailfold capillaroscopy in the diagnosis has not been established yet.

引用

页码：1446 / 1449

页数：4

共 16 条

[1] The clinical manifestations at the onset of antisynthetase syndrome: A chameleon with multiple faces [J].

Baccaro, A. C. C. D. ;

Behrens Pinto, G. L. ;

Carboni, R. C. S. ;

Shinjo, S. K. .

REUMATISMO, 2020, 72 (02) :86-92

[2]

Baeck M., 2018, CASE REPORTS, V2018

[3] ESVM guidelines - the diagnosis and management of Raynaud's phenomenon [J].

Belch, Jill ;

Carlizza, Anita ;

Carpentier, Patrick H. ;

Constans, Joel ;

Khan, Faisel ;

Wautrecht, Jean-Claude ;

Visona, Adriana ;

Heiss, Christian ;

Brodeman, Marianne ;

Pecsvarady, Zsolt ;

Roztocil, Karel ;

Colgan, Mary-Paula ;

Vasic, Dragan ;

Gottsater, Anders ;

Amann-Vesti, Beatrice ;

Chraim, Ali ;

Poredos, Pavel ;

Olinic, Dan-Mircea ;

Madaric, Juraj ;

Nikol, Sigrid ;

Herrick, Ariane L. ;

Sprynger, Muriel ;

Klein-Weigel, Peter ;

Hafner, Franz ;

Staub, Daniel ;

Zeman, Zan .

VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE, 2017, 46 (06) :413-423

[4] Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course [J].

Cavagna, Lorenzo ;

Trallero-Araguas, Ernesto ;

Meloni, Federica ;

Cavazzana, Ilaria ;

Rojas-Serrano, Jorge ;

Feist, Eugen ;

Zanframundo, Giovanni ;

Morandi, Valentina ;

Meyer, Alain ;

Pereira da Silva, Jose Antonio ;

Matos Costa, Carlo Jorge ;

Molberg, Oyvind ;

Andersson, Helena ;

Codullo, Veronica ;

Mosca, Marta ;

Barsotti, Simone ;

Neri, Rossella ;

Scire, Carlo ;

Govoni, Marcello ;

Furini, Federica ;

Javier Lopez-Longo, Francisco ;

Martinez-Barrio, Julia ;

Schneider, Udo ;

Lorenz, Hanns-Martin ;

Doria, Andrea ;

Ghirardello, Anna ;

Ortego-Centeno, Norberto ;

Confalonieri, Marco ;

Tomietto, Paola ;

Pipitone, Nicolo ;

Rodriguez Cambron, Ana Belen ;

Blazquez Canamero, Maria Angeles ;

Voll, Reinhard Edmund ;

Wendel, Sarah ;

Scarpato, Salvatore ;

Maurier, Francois ;

Limonta, Massimiliano ;

Colombelli, Paolo ;

Giannini, Margherita ;

Geny, Bernard ;

Arrigoni, Eugenio ;

Bravi, Elena ;

Migliorini, Paola ;

Mathieu, Alessandro ;

Piga, Matteo ;

Drott, Ulrich ;

Delbrueck, Christiane ;

Bauhammer, Jutta ;

Cagnotto, Giovanni ;

Vancheri, Carlo .

JOURNAL OF CLINICAL MEDICINE, 2019, 8 (11)

[5]

Das Sudip, 2013, Indian J Dermatol, V58, P417, DOI 10.4103/0019-5154.119946

[6] y Raynaud's phenomenon [J].

Herrick, Ariane L. ;

Wigley, Fredrick M. .

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY, 2020, 34 (01)

[7] Hierarchical cluster and survival analyses of antisynthetase syndrome: Phenotype and outcome are correlated with anti-tRNA synthetase antibody specificity [J].

Hervier, Baptiste ;

Devilliers, Herve ;

Stanciu, Raluca ;

Meyer, Alain ;

Uzunhan, Yurdagul ;

Masseau, Agathe ;

Dubucquoi, Sylvain ;

Hatron, Pierre-Yves ;

Musset, Lucile ;

Wallaert, Benoit ;

Nunes, Hilario ;

Maisonobe, Thierry ;

Olsson, Nils-Olivier ;

Adoue, Daniel ;

Arlet, Philippe ;

Sibilia, Jean ;

Guiguet, Marguerite ;

Lauque, Dominique ;

Amoura, Zahir ;

Hachulla, Eric ;

Hamidou, Mohamed ;

Benveniste, Olivier .

AUTOIMMUNITY REVIEWS, 2012, 12 (02) :210-217

[8] Development of a New Classification System for Idiopathic Inflammatory Myopathies Based on Clinical Manifestations and Myositis-Specific Autoantibodies [J].

Mariampillai, Kuberaka ;

Granger, Benjamin ;

Amelin, Damien ;

Guiguet, Marguerite ;

Hachulla, Eric ;

Maurier, Francois ;

Meyer, Alain ;

Tohme, Aline ;

Charuel, Jean-Luc ;

Musset, Lucile ;

Allenbach, Yves ;

Benveniste, Olivier .

JAMA NEUROLOGY, 2018, 75 (12) :1528-1537

[9] Clinical Images: Persistent acrocyanosis-a rare manifestation revealing anti-PL-12 syndrome [J].

Mertz, Philippe ;

Herber, Mathilde ;

Jeannel, Juliette ;

Korganow, Anne-Sophie ;

Guffroy, Aurelien .

ARTHRITIS & RHEUMATOLOGY, 2018, 70 (10) :1698-1698

[10]

Nendaz M., 2018, REV MED SUISSE, V14, P18

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