Validation of a GATE model for the simulation of the Siemens biograph™ 6 PET scanner

被引：53

作者：

Gonias, P.

Bertsekas, N.

Karakatsanis, N.

Saatsakis, G.

Gaitanis, A.

Nikolopoulos, D.

Loudos, G.

Papaspyrou, L.

Sakellios, N.

Tsantilas, X.

Daskalakis, A.

Liaparinos, P.

Nikita, K.

Louizi, A.

Cavouras, D.

Kandarakis, I. ^{[1
]}

Panayiotakis, G. S.

机构：

[1] Univ Patras, Dept Med Phys, Sch Med, Patras 26500, Greece

[2] Technol Educ Inst Athens, Dept Med Instruments Technol, Athens 12210, Greece

[3] Natl Tech Univ Athens, Dept Elect & Comp Engn, Zografos 15780, Greece

[4] Univ Athens, Dept Biomed Engn, Hosp Aretaieion, Athens, Greece

[5] Acad Athens, Fdn Biomed Res, IIBEAA, Athens 11527, Greece

[6] Univ Athens, Dept Phys Med, GR-10679 Athens, Greece

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2007年 / 571卷 / 1-2期

关键词：

validation GATE; PET; Monte Carlo simulations; biograph; 6; NEMA NU 2-2001;

D O I：

10.1016/j.nima.2006.10.078

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

The recently developed Geant4 Application for Tomographic Emission (GATE) toolkit is a Monte Carlo simulation platform developed for PET and SPECT simulations and is freely distributed by the OpenGATE collaboration. GATE provides the ability of modelling time-dependent phenomena, such as geometry element movements and source decay kinetics, allowing the simulation of time curves under realistic acquisition conditions. The purpose of this paper was to validate a GATE model for the simulation of the Siemens PET Biograph (TM) 6 scanner. This three-dimensional GATE model simulated 24336 LSO (Lutetium Oxyorthosilicate) detectors grouped into 144 blocks in accordance with the vendor's specifications. GATE results were compared with experimental data, obtained in accordance with the NEMA NU 2-2001 performance measurement protocol. The scatter phantom used by this protocol was also modelled within GATE, allowing us to simulate scatter fraction and count rate performance measurements. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：263 / 266

页数：4

共 7 条

[1] GEANT4-a simulation toolkit [J].

Agostinelli, S ;

Allison, J ;

Amako, K ;

Apostolakis, J ;

Araujo, H ;

Arce, P ;

Asai, M ;

Axen, D ;

Banerjee, S ;

Barrand, G ;

Behner, F ;

Bellagamba, L ;

Boudreau, J ;

Broglia, L ;

Brunengo, A ;

Burkhardt, H ;

Chauvie, S ;

Chuma, J ;

Chytracek, R ;

Cooperman, G ;

Cosmo, G ;

Degtyarenko, P ;

Dell'Acqua, A ;

Depaola, G ;

Dietrich, D ;

Enami, R ;

Feliciello, A ;

Ferguson, C ;

Fesefeldt, H ;

Folger, G ;

Foppiano, F ;

Forti, A ;

Garelli, S ;

Giani, S ;

Giannitrapani, R ;

Gibin, D ;

Cadenas, JJG ;

González, I ;

Abril, GG ;

Greeniaus, G ;

Greiner, W ;

Grichine, V ;

Grossheim, A ;

Guatelli, S ;

Gumplinger, P ;

Hamatsu, R ;

Hashimoto, K ;

Hasui, H ;

Heikkinen, A ;

Howard, A .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2003, 506 (03) :250-303

[2] ROOT - An object oriented data analysis framework [J].

Brun, R ;

Rademakers, F .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 389 (1-2) :81-86

[3]

Daube-Witherspoon ME, 2002, J NUCL MED, V43, P1398

[4] GATE:: a simulation toolkit for PET and SPECT [J].

Jan, S ;

Santin, G ;

Strul, D ;

Staelens, S ;

Assié, K ;

Autret, D ;

Avner, S ;

Barbier, R ;

Bardiès, M ;

Bloomfield, PM ;

Brasse, D ;

Breton, V ;

Bruyndonckx, P ;

Buvat, I ;

Chatziioannou, AF ;

Choi, Y ;

Chung, YH ;

Comtat, C ;

Donnarieix, D ;

Ferrer, L ;

Glick, SJ ;

Groiselle, CJ ;

Guez, D ;

Honore, PF ;

Kerhoas-Cavata, S ;

Kirov, AS ;

Kohli, V ;

Koole, M ;

Krieguer, M ;

van der Laan, DJ ;

Lamare, F ;

Largeron, G ;

Lartizien, C ;

Lazaro, D ;

Maas, MC ;

Maigne, L ;

Mayet, F ;

Melot, F ;

Merheb, C ;

Pennacchio, E ;

Perez, J ;

Pietrzyk, U ;

Rannou, FR ;

Rey, M ;

Schaart, DR ;

Schmidtlein, CR ;

Simon, L ;

Song, TY ;

Vieira, JM ;

Visvikis, D .

PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (19) :4543-4561

[5] Validation of a Monte Carlo simulation of the Philips Allegro/GEMINI PET systems using GATE [J].

Lamare, F ;

Turzo, A ;

Bizais, Y ;

Le Rest, CC ;

Visvikis, D .

PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (04) :943-962

[6]

National Electrical Manufactures Association, 2001, NEMA STAND PUBL NU

[7] Validation of GATE Monte Carlo simulations of the GE Advance/Discovery LS PET scanners [J].

Schmidtlein, CR ;

Kirov, AS ;

Nehmeh, SA ;

Erdi, YE ;

Humm, JL ;

Amols, HI ;

Bidaut, LM ;

Ganin, A ;

Stearns, CW ;

McDaniel, DL ;

Hamacher, KA .

MEDICAL PHYSICS, 2006, 33 (01) :198-208

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