Atopic dermatitis

被引:1101
作者
Leung, DYM
Bieber, T
机构
[1] Natl Jewish Med & Res Ctr, Div Pediat Allergy & Immunol, Denver, CO 80206 USA
[2] Univ Colorado, Hlth Sci Ctr, Dept Pediat, Denver, CO 80262 USA
[3] Univ Bonn, Dept Dermatol, D-5300 Bonn, Germany
关键词
D O I
10.1016/S0140-6736(03)12193-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10-20% of children worldwide. Symptoms can persist or begin in adulthood. It is also the most common cause of occupational skin disease in adults. This disease results from an interaction between susceptibility genes, the host's environment, pharmacological abnormalities, skin barrier defects, and immunological factors. New management approaches have evolved from advances in our understanding of the pathobiology of this common skin disorder.
引用
收藏
页码:151 / 160
页数:10
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