Mathematical descriptors of DNA sequences: development and applications

被引:133
作者
Nandy, Ashesh [1 ]
Harle, Marissa [1 ]
Basak, Subhash C. [1 ]
机构
[1] Univ Minnesota, Nat Resources Res Inst, 5013 Miller Trunk Highway, Duluth, MN 55811 USA
关键词
graphical representation; numerical characterization; mathematical descriptors; DNA sequences;
D O I
10.3998/ark.5550190.0007.907
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Over the last few years several authors have presented various methods to assign mathematical descriptors to DNA sequences in order to quantitatively compare the sequences and determine similarities and dissimilarities between them. The plethora of different methods used have made it necessary to compare them and determine which one(s), if any, best meet the needs required to characterize DNA sequences. With the very rapid rise in available DNA sequence data and the strong need for robust quantitative techniques to determine regions of interest in these sequences, numerical characterization of DNA and RNA sequences will be of great importance in filling a part of this need.
引用
收藏
页码:211 / 238
页数:28
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