HIV Pre-exposure Prophylaxis and Buprenorphine at a Drug Detoxification Center During the Opioid Epidemic: Opportunities and Challenges

被引：13

作者：

Assoumou, Sabrina A. ^{[1
,2
]}

Paniagua, Samantha M. ^{[2
]}

Gonzalez, Priscilla ^{[3
]}

Wang, Jianing ^{[2
]}

Beckwith, Curt G. ^{[4
,5
]}

White, Laura F. ^{[6
]}

Taylor, Jessica L. ^{[7
,8
,9
]}

Coogan, Kristen ^{[10
]}

Samet, Jeffrey H. ^{[7
,8
,11
]}

Linas, Benjamin P. ^{[1
,2
,11
]}

机构：

[1] Boston Univ, Sch Med, Dept Med, Sect Infect Dis,Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[2] Boston Med Ctr, Sect Infect Dis, Dept Med, Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[3] Boston Univ, Sch Med, 72 East Concord St, Boston, MA 02118 USA

[4] Brown Univ, Dept Med, Alpert Med Sch, Div Infect Dis, Providence, RI 02912 USA

[5] Miriam Hosp, Providence, RI 02906 USA

[6] Boston Univ, Sch Publ Hlth, Dept Biostat, 801 Mass Ave,3rd Floor, Boston, MA 02118 USA

[7] Boston Med Ctr, Dept Med, Sect Gen Internal Med, Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[8] Boston Univ, Sch Med, Dept Med, Sect Gen Internal Med,Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[9] Boston Med Ctr, Grayken Ctr Addict, Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

[10] Boston Univ, Coll Fine Arts, 808 Commonwealth Ave,4th Floor, Boston, MA 02215 USA

[11] Boston Univ, Sch Publ Hlth, Crosstown Ctr, 801 Massachusetts Ave,2nd Floor, Boston, MA 02118 USA

来源：

AIDS AND BEHAVIOR | 2021年 / 25卷 / 08期

关键词：

Pre-exposure prophylaxis; Persons who inject drugs; Human immunodeficiency virus; Medication for opioid use disorder; Drug detoxification center;

D O I：

10.1007/s10461-021-03220-0

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) and buprenorphine decrease HIV acquisition. Between November, 2016 and July, 2017, we surveyed persons (N = 200) at a drug detoxification center to assess their interest in PrEP and in buprenorphine, and to examine factors associated with such interests. Over the previous 6 months, 58% (117/200) injected drugs, 87% (173/200) used opioids, 50% (85/171) had condomless sex. Only 22% (26/117) of persons who injected drugs were aware of PrEP, yet 74% (86/116) and 72% (84/116) were interested in oral or injectable PrEP, respectively. Thirty-eight percent (47/125) of persons not receiving buprenorphine or methadone expressed interest in buprenorphine. After multivariable adjustment, Latinx ethnicity was associated with interest in PrEP (aOR 3.80; 95% CI 1.37-10.53), while male gender (aOR 2.76; 95% CI 1.21-6.34) was associated with interest in buprenorphine. Opportunities exist to implement PrEP and buprenorphine within drug detoxification centers. Clinical trial registration NCT02869776. Clinicaltrials.gov.

引用

页码：2591 / 2598

页数：8

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