Antimicrobial prophylaxis to prevent surgical site infections in a rural sub-Saharan hospital

被引:19
作者
Fehr, J.
Hatz, C.
Soka, I.
Kibatala, P.
Urassa, H.
Battegay, M.
Jeffrey, Z.
Smith, T.
Mshinda, H.
Frei, R.
Widmer, A. F.
机构
[1] Univ Basel Hosp, Div Infect Dis & Hosp Epidemiol, CH-4031 Basel, Switzerland
[2] Swiss Trop Inst, Dept Med & Diagnost, CH-4002 Basel, Switzerland
[3] St Francis Designated Dist Hosp, Ifakara, Tanzania
[4] Hlth Res & Dev Ctr, Ifakara, Tanzania
[5] Univ Basel Hosp, Microbiol Lab, CH-4031 Basel, Switzerland
关键词
antimicrobial prophylaxis; developing countries; nosocomial infection; perioperative; surgical site infection; Tanzania;
D O I
10.1111/j.1469-0691.2006.01551.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A prospective cohort study was performed to collect baseline data concerning surgical site infections (SSIs) and antimicrobial prophylaxis (AMP) in a remote sub-Saharan district hospital. The SSI rate of 22% was high. Most (88%) of the patients received prophylaxis after incision, and only 5% within the 30-min period before incision. Of all pathogens isolated from SSIs, 60% were resistant to the agent administered. The antibiotics given most frequently were chloramphenicol (60%), aminopenicillins (23%) and benzylpenicillin (15%). Staphylococcus aureus (36%), Escherichia coli (5%) and enterococci (4%) were the pathogens isolated most commonly from SSIs.
引用
收藏
页码:1224 / 1227
页数:4
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