An efficient reduction of nitro and bromine naphthalene derivatives

被引：1

作者：

Dong, J. ^{[1
]}

Zhang, Q. ^{[1
]}

Huang, G. ^{[1
]}

Meng, Q. ^{[1
]}

Li, S. ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Pharm, 800 Dongchuan Rd, Shanghai 200240, Peoples R China

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2017年 / 87卷 / 04期

基金：

中国博士后科学基金;

关键词：

nitro naphthalenes; reduction; naphthylamines; hydrazine hydrate; zinc powder; FLUORESCENT-PROBE; HYDROGENATION; NITROARENES; INHIBITORS; CATALYST;

D O I：

10.1134/S1070363217040272

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reduction of 1,5-dimethoxy-4-nitronaphthalene by hydrazine hydrate was optimized in the course of current study. Influence of metals, temperature and solvents upon the process was tested. Yield of the reaction was the highest in the presence of Zn powder in DMF. Moderate heating made the process slightly more efficient than that at room temperature, whereas high temperature led to a decreased yield. The current approach made it possible to exclude high pressure and diminish experimental costs.

引用

页码：837 / 841

页数：5

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