Optimization of LSO LuYAP phoswich detector for small animal PET

被引:40
作者
Jung, Jin Ho
Choi, Yong [1 ]
Chung, Yong Hyun
Devroede, Olivier
Krieguer, Magalie
Bruyndonckx, Peter
Tavernier, Stefaan
机构
[1] Sungkyunkwan Univ, Sch Med, Dept Nucl Med, Samsung Med Ctr, Seoul 135710, South Korea
[2] Yonsei Univ, Coll Hlth Sci, Dept Radiol Sci, Wonju 220710, South Korea
[3] Vrije Univ Brussel, Inter Univ Inst High Energies, B-1050 Brussels, Belgium
关键词
small animal PET; phoswich detectors; optical coupling; depth of interaction;
D O I
10.1016/j.nima.2006.10.293
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
LSO/LuYAP phoswich detectors for small animal PET were developed to measure the depth of interaction (DOI), and to improve the spatial resolution at the edge of the field of view (FOV). The aim of this study was to optimize the optical coupling conditions between the crystal and photomultiplier tube (PMT) to maximize the light-collection efficiency, and to develop a method for rejecting scatter events by applying an equal energy window in each crystal layer. The light yields of the phoswich detector were estimated by changing the refractive index of the optical coupling material using a DETECT simulation. The accuracy of the DOI measurement on the phoswich detector, using an optical coupling, material with the optimal light yield, were evaluated experimentally and compared with the air condition. The energy window for the photopeak events cannot be applied property because the light outputs of LSO and LuYAP are different. The LSO/LuYAP photopeaks need to be superposed in order to effectively discriminate the scattered events by applying an equal energy window. The photopeaks of the LSO and LuYAP can be Superposed by inserting a reflecting material between the crystals. The optimal coverage ratio of the inserting material was derived from a DETECT simulation, and its performance was investigated. In I he simulation result, optimal refractive index of the Optical Coupling material was 1.7. The average DOI measurement errors of the LSO/ LuYAP were 0.6%/3.4% and 4.9%/41.4% in the phoswich detector with and without an optical coupling material, respectively. The photopeaks of the LSO and LuYAP were superposed by covering 75% ( of the contact surface between the crystals with white Teflon. The DOI measurement errors of the LSO/LuYAP were 0.2%/2.4%). In this study, the optimal condition of the optical coupling material inserted between the crystal and PMT was derived to improve the accuracy of DOI measurement, and a photopeak superposition method of the LSO and LuYAP was developed in order to reject scatter events.
引用
收藏
页码:669 / 675
页数:7
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