Zinc doped copper ferrite particles as temperature sensors for magnetic resonance imaging

被引:22
作者
Hankiewicz, Janusz H. [1 ]
Alghamdi, Noweir [1 ]
Hammelev, Nicholas M. [2 ]
Anderson, Nick R. [1 ]
Camley, Robert E. [1 ]
Stupic, Karl [3 ]
Przybylski, Marek [4 ,5 ]
Zukrowski, Jan [5 ]
Celinski, Zbigniew J. [1 ]
机构
[1] UCCS BioFrontiers Ctr, 1420 Austin Bluffs Pkwy, Colorado Springs, CO 80918 USA
[2] Colorado Sch Mines, Dept Engn Phys, 1500 Illinois St, Golden, CO 80401 USA
[3] NIST, Boulder, CO 80305 USA
[4] AGH Univ Sci & Technol, Acad Ctr Mat & Nanotechnol, PL-30059 Krakow, Poland
[5] AGH Univ Sci & Technol, Fac Phys & Appl Comp Sci, PL-30059 Krakow, Poland
关键词
NANOPARTICLES; THERMOMETRY; TRANSDUCERS; CANCER; MRI;
D O I
10.1063/1.4973439
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
We investigate the use of Cu0.35Zn0.65Fe2O4 particles as temperature-dependent sensors in magnetic resonance imaging (MRI). This material has a Curie temperature near 290 K, but in the large magnetic fields found in MRI scanners, there is a significant temperature-dependent magnetic moment near body temperature; 310 K. When the ferrite particles are doped into an agar gel, the temperature-dependent magnetic moment leads to a temperature-dependent broadening of the NMR linewidth for water protons and to a temperature-dependent image intensity for MRI, allowing one to make temperature maps within objects. The temperature resolution is about 1.3 K. (C) 2016 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
引用
收藏
页数:6
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