Asymmetric organocatalytic synthesis of cis-substituted dihydrobenzofuranols via intramolecular aldol reactions

被引：46
作者：
Enders, Dieter
Niemeier, Oliver
Straver, Leo
机构：
[1] Univ Aachen, Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
[2] Bruker AXS BV, Applicat SCD, NL-2600 AV Delft, Netherlands
来源：
SYNLETT | 2006年 / 20期
关键词：
organocatalysis; aldol reaction; asymmetric synthesis; proline; dihydrobenzofuran;
D O I：
10.1055/s-2006-956454
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The diastereo- and enantioselective synthesis of 3-hydroxy 2.3-dihydrobenzofurans via an intramolecular cis-selective aldol reaction employing proline-type organocatalysts is described enabling a new entry to coumarine natural products.
引用
收藏
页码：3399 / 3402
页数：4
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