Cardiovascular health in an aging HIV population

被引:18
作者
Boccara, Franck [1 ]
机构
[1] UPMC, St Antoine Univ Hosp, AP HP, Div Cardiol,INSERM,UMR S 938, Paris, France
关键词
aging; cardiovascular disease; dyslipidemia; HIV; hypertension; ACUTE MYOCARDIAL-INFARCTION; IMMUNODEFICIENCY-VIRUS PATIENTS; ACUTE CORONARY SYNDROME; DISEASE RISK-FACTORS; ANTIRETROVIRAL THERAPY; INFECTED PATIENTS; POSITIVE INDIVIDUALS; BLOOD-PRESSURE; HEART-DISEASE; HYPERTENSION;
D O I
10.1097/QAD.0000000000001384
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Populations living with HIV who access effective antiretroviral therapies are ageing and thus facing chronic disease-related comorbidities. Cardiovascular disease is now a leading cause of morbidity and mortality in the HIV population as in the general population. The increased incidence of cardiovascular complications experienced by the HIV population is due to physiological aging and consequently the increased risk of hypertension, diabetes, and renal failure. Whether HIV itself is an additive and independent risk factor for cardiovascular disease (CVD) remains a central question. If and how HIV impacts the ageing process is an important and related question. The purpose of the present review is to highlight the risk of CVD in the ageing HIV population, particularly concerning atherosclerotic CVD (ASCVD) and heart failure, and to address effective CVD prevention in an aging HIV population at risk of poly-pharmacy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:S157 / S163
页数:7
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