Diffusion-weighted imaging in acute stroke -: A tool of uncertain value?

被引：41
作者：
Fiehler, J
Fiebach, JB
Gass, A
Hoehn, M
Kucinski, T
Neumann-Haefelin, T
Schellinger, PD
Siebler, M
Villringer, A
Röther, J
机构：
[1] Univ Hamburg, Hosp Eppendorf, Dept Neuroradiol, D-20246 Hamburg, Germany
[2] Univ Heidelberg Hosp, Dept Neuroradiol, Heidelberg, Germany
[3] Univ Heidelberg Hosp, Dept Neurol, Heidelberg, Germany
[4] Univ Hosp Frankfurt, Dept Neurol, Frankfurt, Germany
[5] Univ Hosp Dusseldorf, Dept Neurol, Dusseldorf, Germany
[6] Univ Hosp Berlin, Charite, Dept Neurol, Berlin, Germany
[7] Univ Hosp Hamburg Eppendorf, Dept Neurol, Hamburg, Germany
[8] Max Planck Inst Expt Neurol, Cologne, Germany
来源：
CEREBROVASCULAR DISEASES | 2002年 / 14卷 / 3-4期
关键词：
stroke; magnetic resonance imaging; diffusion;
D O I：
10.1159/000065675
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The concept of a mismatch between the lesion volume in diffusion- and perfusion-weighted magnetic resonance imaging (MRI) indicating 'tissue at risk of infarction' is based on the assumption that tissue with diffusion slowing in diffusion-weighted MRI (DWI) or decreased values of the apparent diffusion coefficient represents irreversibly damaged tissue. Recent experimental as well as clinical studies, however, have shown that tissue with diffusion slowing may well normalize if the hypoperfusion is moderate or transient. We will interpret these findings in the light of experimental data and suggest a way for the interpretation of different time courses of lesion development in DWI within a clinical MRI protocol. MR stroke imaging delivers important information in acute stroke, particularly in defining the 'tissue at risk of infarction'. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码：187 / 196
页数：10
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