Fading spectrophotometric method for the determination of raloxifene with evans blue

被引:0
作者
Qin, ZH
Fan, L
Liu, SP [1 ]
Jiang, H
机构
[1] SW China Normal Univ, Inst Environm Chem, Chongqing 400715, Peoples R China
[2] Fuling Teachers Coll, Dept Chem, Fuling 408003, Peoples R China
关键词
spectrophotometric method; raloxifene; evans blue;
D O I
暂无
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
In sodium acetate-hydrochloric acid buffer solution at pH 1.4 similar to 2.5, raloxifene (Ralo) reacts with evans blue (EB) to form an ion-association complex, which make the EB fade. The measurement wavelength for the spectrophotometric deermination of Ralo is at 610 nm. Beer's law is obeyed in the range of 0 similar to 1.4 x 10(-5) mol/L, and the apparent molar absorptivity epsilon(610) is 1.76 x 10(4) L.mol(-1).cm(-1). The method has high sensitivity and fairly good selectivity.
引用
收藏
页码:1486 / 1489
页数:4
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