Could targeting immunometabolism be a way to control the burden of COVID-19 infection?

被引：9

作者：

Berber, Engin ^{[1
,2
]}

Sumbria, Deepak ^{[1
]}

Rouse, Barry T. ^{[1
]}

机构：

[1] Univ Tennessee, Coll Vet Med, Dept Biomed & Diagnost Sci, Knoxville, TN USA

[2] Erciyes Univ, Fac Vet Med, Dept Virol, Kayseri, Turkey

来源：

MICROBES AND INFECTION | 2021年 / 23卷 / 2-3期

关键词：

SARS-Cov-2; Covid-19; Immunometabolism; Metabolic disease; Nutrition; Anti-metabolite therapy; GUT MICROBIOTA; DIETARY FIBER; GLUCOSE; HYPERGLYCEMIA; SARS-COV-2; MICE; FAT;

D O I：

10.1016/j.micinf.2021.104780

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This review portrays the metabolic consequences of Covid-19 infection at different stages of the clinical syndrome. It also describes how events can change when patients with metabolic problems are infected and the effects that diet and nutrition might play to influence the outcome of infection. We also discuss the types of maneuvers that could be used to reshape metabolic events and question if this approach could be a practical therapy used alone or in combination with other approaches to reduce the burden of Covid-19 infection. (c) 2021 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

引用

页数：7

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