Immortal Time Bias in Observational Studies

被引：263

作者：

Yadav, Kabir ^{[1
,2
,3
]}

Lewis, Roger J. ^{[1
,2
,3
,4
]}

机构：

[1] Harbor UCLA Med Ctr, Dept Emergency Med, 1000 W Carson St,Bldg D9, Torrance, CA 90509 USA

[2] Lundquist Inst, Torrance, CA USA

[3] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA

[4] Berry Consultants LLC, Austin, TX USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 2021年 / 325卷 / 07期

关键词：

D O I：

10.1001/jama.2020.9151

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This JAMA Guide to Statistics and Medicine explains immortal time bias, an error in estimating the association between an exposure and an outcome that results from misclassification or exclusion of time intervals; explains how this misclassification or exclusion can occur; and presents approaches to minimize or avoid immortal time bias.

引用

页码：686 / 687

页数：2

共 4 条

[1] Specifying a target trial prevents immortal time bias and other self-inflicted injuries in observational analyses [J].

Hernan, Miguel A. ;

Sauer, Brian C. ;

Hernandez-Diaz, Sonia ;

Platt, Robert ;

Shrier, Ian .

JOURNAL OF CLINICAL EPIDEMIOLOGY, 2016, 79 :70-75

[2] Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease [J].

Honigberg, Michael C. ;

Zekavat, Seyedeh Maryam ;

Aragam, Krishna ;

Finneran, Phoebe ;

Klarin, Derek ;

Bhatt, Deepak L. ;

Januzzi, James L., Jr. ;

Scott, Nandita S. ;

Natarajan, Pradeep .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019, 322 (24) :2411-2421

[3] Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes [J].

Levesque, Linda E. ;

Hanley, James A. ;

Kezouh, Abbas ;

Suissa, Samy .

BRITISH MEDICAL JOURNAL, 2010, 340 :907-911

[4] Immortal time bias in pharmacoepidemiology [J].

Suissa, Samy .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2008, 167 (04) :492-499

← 1 →