The synthesis of 1,2,4-benzotriazines

被引：5

作者：

Ziarani, Ghodsi Mohammadi ^{[1
]}

Mostofi, Madine ^{[1
]}

Gholamzadeh, Parisa ^{[1
]}

Mohammadi-Khanaposhtani, Maryam ^{[2
]}

Yavari, Hossein ^{[3
,4
]}

机构：

[1] Alzahra Univ, Dept Chem, Vanak Sq,POB 1993893973, Tehran, Iran

[2] Babol Univ Med Sci, Cellular & Mol Biol Res Ctr, Hlth Res Inst, POB 4717647745, Babol Sar, Iran

[3] Univ Tehran Med Sci, Fac Pharm, Dept Med Chem, POB 14176, Tehran, Iran

[4] Univ Tehran Med Sci, Pharmaceut Sci Res Ctr, POB 14176, Tehran, Iran

来源：

ARKIVOC | 2019年

关键词：

1,2,4-Benzotriazines; 1,2,4-benzotriazine N-oxides; 1,2,4-benzotriazine 1,4-dioxides; 3-amino-1,2,4-benzotriazine N-oxides; BENZOTRIAZINE BASED COMPOUNDS; CROSS-COUPLING REACTIONS; 1,2,4-TRIAZINE DERIVATIVES; ANTITUMOR-ACTIVITY; RING CONTRACTION; 1,4-DIOXIDES; ACID; TIRAPAZAMINE; CYCLIZATION; AGENT;

D O I：

10.24820/ark.5550190.p010.791

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 1,2,4-benzotriazine nucleus fused to a benzene ring is a prominent heterocyclic substructure present in numerous pharmacologically active compounds. To date, many 1,2,4-benzotriazine analogues possessing a wide spectrum of potent pharmacological activities are known. This review compiles information on the synthesis, chemical reactions, medicinal chemistry aspects and applications of 1,2,4-benzotriazines. [GRAPHICS] .

引用

页码：41 / 105

页数：65

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