Antibacterial properties and toxicity from metallic nanomaterials

被引:434
作者
Vimbela, Gina V. [1 ]
Ngo, Sang M. [2 ]
Fraze, Carolyn [3 ]
Yang, Lei [4 ,5 ]
Stout, David A. [5 ,6 ,7 ]
机构
[1] Calif State Univ Long Beach, Dept Chem Engn, Long Beach, CA 90840 USA
[2] Calif State Univ Long Beach, Dept Elect Engn, Long Beach, CA 90840 USA
[3] Brigham Young Univ Idaho, Rexburg, ID USA
[4] Soochow Univ, Affiliated Hosp 1, Orthopaed Inst, Dept Orthopaed, Suzhou, Jiangsu, Peoples R China
[5] Soochow Univ, IRCTO, Suzhou, Jiangsu, Peoples R China
[6] Calif State Univ Long Beach, Dept Mech & Aerosp Engn, 1250 Bellflower Blvd,ECS 632 Long Beach, Long Beach, CA 90840 USA
[7] Calif State Univ Long Beach, Dept Biomed Engn, Long Beach, CA 90840 USA
来源
INTERNATIONAL JOURNAL OF NANOMEDICINE | 2017年 / 12卷
基金
中国国家自然科学基金; 美国国家卫生研究院;
关键词
antibacterial reagents; nanomaterials; synthesis; metals; nanostructure; nanoscale; antibiotic resistance; toxicity; drug delivery; ZINC-OXIDE NANOPARTICLES; SURFACE-PLASMON RESONANCE; MEDIATED GREEN SYNTHESIS; MESENCHYMAL STEM-CELLS; SILVER NANOPARTICLES; GOLD NANOPARTICLES; TITANIUM-DIOXIDE; ANTIMICROBIAL ACTIVITY; COPPER NANOPARTICLES; AQUATIC TOXICITY;
D O I
10.2147/IJN.S134526
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The era of antibiotic resistance is a cause of increasing concern as bacteria continue to develop adaptive countermeasures against current antibiotics at an alarming rate. In recent years, studies have reported nanoparticles as a promising alternative to antibacterial reagents because of their exhibited antibacterial activity in several biomedical applications, including drug and gene delivery, tissue engineering, and imaging. Moreover, nanomaterial research has led to reports of a possible relationship between the morphological characteristics of a nanomaterial and the magnitude of its delivered toxicity. However, conventional synthesis of nanoparticles requires harsh chemicals and costly energy consumption. Additionally, the exact relationship between toxicity and morphology of nanomaterials has not been well established. Here, we review the recent advancements in synthesis techniques for silver, gold, copper, titanium, zinc oxide, and magnesium oxide nanomaterials and composites, with a focus on the toxicity exhibited by nanomaterials of multidimensions. This article highlights the benefits of selecting each material or metal-based composite for certain applications while also addressing possible setbacks and the toxic effects of the nanomaterials on the environment.
引用
收藏
页码:3941 / 3965
页数:25
相关论文
共 145 条
  • [1] Antimicrobial wound dressing nanofiber mats from multicomponent (chitosan/silver-NPs/polyvinyl alcohol) systems
    Abdelgawad, Abdelrahman M.
    Hudson, Samuel M.
    Rojas, Orlando J.
    [J]. CARBOHYDRATE POLYMERS, 2014, 100 : 166 - 178
  • [2] Immobilized silver nanoparticles enhance contact killing and show highest efficacy: elucidation of the mechanism of bactericidal action of silver
    Agnihotri, Shekhar
    Mukherji, Soumyo
    Mukherji, Suparna
    [J]. NANOSCALE, 2013, 5 (16) : 7328 - 7340
  • [3] Preparation of gold nanoparticles using Salicornia brachiata plant extract and evaluation of catalytic and antibacterial activity
    Ahmed, Khan Behlol Ayaz
    Subramanian, Swetha
    Sivasubramanian, Aravind
    Veerappan, Ganapathy
    Veerappan, Anbazhagan
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2014, 130 : 54 - 58
  • [4] Cu and CuO nanoparticles immobilized by silica thin films as antibacterial materials and photocatalysts
    Akhavan, O.
    Ghaderi, E.
    [J]. SURFACE & COATINGS TECHNOLOGY, 2010, 205 (01) : 219 - 223
  • [5] Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species
    Akhtar, Mohd Javed
    Ahamed, Maqusood
    Kumar, Sudhir
    Khan, M. A. Majeed
    Ahmad, Javed
    Alrokayan, Salman A.
    [J]. INTERNATIONAL JOURNAL OF NANOMEDICINE, 2012, 7 : 845 - 857
  • [6] Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity
    Albanese, Alexandre
    Chan, Warren C. W.
    [J]. ACS NANO, 2011, 5 (07) : 5478 - 5489
  • [7] In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations
    Albers, Christoph E.
    Hofstetter, Wilhelm
    Siebenrock, Klaus A.
    Landmann, Regine
    Klenke, Frank M.
    [J]. NANOTOXICOLOGY, 2013, 7 (01) : 30 - 36
  • [8] Updated Global Burden of Cholera in Endemic Countries
    Ali, Mohammad
    Nelson, Allyson R.
    Lopez, Anna Lena
    Sack, David A.
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2015, 9 (06):
  • [9] Copper oxide nanomaterials: Synthesis, characterization and structure-specific antibacterial performance
    Ananth, Antony
    Dharaneedharan, Subramanian
    Heo, Moon-Soo
    Mok, Young Sun
    [J]. CHEMICAL ENGINEERING JOURNAL, 2015, 262 : 179 - 188
  • [10] Green synthesis, characterization and antimicrobial activity of Au NPs using Euphorbia hirta L. leaf extract
    Annamalai, A.
    Christina, V. L. P.
    Sudha, D.
    Kalpana, M.
    Lakshmi, P. T. V.
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2013, 108 : 60 - 65