Strategy for the Practice of Spine Oncological Surgery During the Covid-19 Pandemic

被引:6
作者
Berjano, Pedro [1 ]
Vanni, Daniele [1 ]
Fariselli, Laura [2 ]
Cecchinato, Riccardo [1 ]
Boriani, Stefano [1 ]
机构
[1] IRCCS Ist Ortoped Galeazzi, Spine Surg Div GSpine4, I-20161 Milan, Italy
[2] IRCCS Ist Neurol Carlo Besta, Radiotherapy Unit, Milan, Italy
关键词
clinical-practice guidelines; Covid-19; pandemic; radiotherapy; spine oncology; spine surgical treatment; spine tumors; INSTABILITY; OSTEOSARCOMA; MANAGEMENT; RECURRENCE; DISEASE;
D O I
10.1097/BRS.0000000000003623
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design. Case series. Objective. For each of the most frequent clinical scenarios, the authors reached a consensus on how should be timing and indications be optimized to reduce risk while maintaining the expected outcomes under the Covid-19 pandemics. Summary of Background Data. The organization of health care has been changed by the Covid-19 pandemic with a direct impact on Spine Oncology Surgery. Emergency surgery is still a priority, but in case of spinal tumors it should be better defined which conditions require emergency treatment. Methods. An expert panel with general spine surgeons, oncological spine surgeons, and radiation oncologists was formed to analyze the most frequent scenarios in spinal musculoskeletal oncology during Covid-19 pandemics. Results. Spine metastases can be found incidentally during follow-up or can clinically occur by increasing pain, pathologic fracture, and/or neurological symptoms. Primary spine tumors are much more rare and very rarely present with acute onset. The first step is to suspect this rare condition, to avoid to treat a primary tumor as it were a metastasis. Most complex surgery, like en bloc resection, associated with high morbidity and mortality rate for the treatment of low grade malignancy like chordoma or chondrosarcomas, if intensive care unit availability is reduced, can be best delayed some weeks, as not impacting on prognosis, due to the slow growth rate of these conditions. The currently accepted protocols for Ewing sarcoma (ES) and osteogenic sarcoma must be performed for local and systemic disease control. For ES, after the first courses of chemotherapy, radiotherapy can be selected instead of surgery, during Covid-19, to the end of the full course of chemotherapy. In immunocompromised patients, (treated by chemotherapy), it is necessary to avoid contact with affected or exposed people. Conclusion. Even more than during normal times, a multidisciplinary approach is mandatory to share the decision to modify a treatment strategy.
引用
收藏
页码:1386 / 1394
页数:9
相关论文
共 48 条
[1]   Aneurysmal bone cyst of the mobile spine: the therapeutic role of embolization [J].
Amendola, L. ;
Simonetti, L. ;
Simoes, C. E. ;
Bandiera, S. ;
De Iure, F. ;
Boriani, S. .
EUROPEAN SPINE JOURNAL, 2013, 22 (03) :533-541
[2]   Spine Instability Neoplastic Score: agreement across different medical and surgical specialties [J].
Arana, Estanislao ;
Kovacs, Francisco M. ;
Royuela, Ana ;
Asenjo, Beatriz ;
Perez-Ramirez, Ursula ;
Zamora, Javier .
SPINE JOURNAL, 2016, 16 (05) :591-599
[3]   Aneurysmal bone cyst of the spine treated by concentrated bone marrow: clinical cases and review of the literature [J].
Barbanti-Brodano, Giovanni ;
Girolami, Marco ;
Ghermandi, Riccardo ;
Terzi, Silvia ;
Gasbarrini, Alessandro ;
Bandiera, Stefano ;
Boriani, Stefano .
EUROPEAN SPINE JOURNAL, 2017, 26 (01) :S158-S166
[4]   Association of neurologic deficits with surgical outcomes and health-related quality of life after treatment for metastatic epidural spinal cord compression [J].
Barzilai, Ori ;
Versteeg, Anne L. ;
Goodwin, C. Rory ;
Sahgal, Arjun ;
Rhines, Laurence D. ;
Sciubba, Daniel M. ;
Schuster, James M. ;
Weber, Michael H. ;
Lazary, Aron ;
Fehlings, Michael G. ;
Clarke, Michelle J. ;
Arnold, Paul M. ;
Boriani, Stefano ;
Bettegowda, Chetan ;
Gokaslan, Ziya L. ;
Fisher, Charles G. ;
Laufer, Ilya .
CANCER, 2019, 125 (23) :4224-4231
[5]   Essential Concepts for the Management of Metastatic Spine Disease: What the Surgeon Should Know and Practice [J].
Barzilai, Ori ;
Boriani, Stefano ;
Fisher, Charles G. ;
Sahgal, Arjun ;
Verlaan, Jorrit Jan ;
Gokaslan, Ziya L. ;
Lazary, Aron ;
Bettegowda, Chetan ;
Rhines, Laurence D. ;
Laufer, Ilya .
GLOBAL SPINE JOURNAL, 2019, 9 :98S-107S
[6]   Reliability analysis of the epidural spinal cord compression scale Clinical article [J].
Bilsky, Mark H. ;
Laufer, Ilya ;
Fourney, Daryl R. ;
Groff, Michael ;
Schmidt, Meic H. ;
Varga, Peter Paul ;
Vrionis, Frank D. ;
Yamada, Yoshiya ;
Gerszten, Peter C. ;
Kuklo, Timothy R. .
JOURNAL OF NEUROSURGERY-SPINE, 2010, 13 (03) :324-328
[7]  
Boriani S, 2011, EUR REV MED PHARMACO, V15, P831
[8]  
Boriani S, 2009, Semin Spine Surg, V21, P76
[9]  
Boriani S., 2015, SPINE J, V15, pS65
[10]  
Boriani Stefano, 2018, J Spine Surg, V4, P668, DOI 10.21037/jss.2018.09.02