How do I manage a patient with enterococcal bacteraemia?

被引:49
作者
Del Turco, Elena Rosselli [1 ]
Bartoletti, Michele [1 ]
Dahl, Anders [2 ]
Cervera, Carlos [3 ]
Pericas, Juan M. [4 ,5 ]
机构
[1] Univ Bologna, St Orsola Malpighi Hosp, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy
[2] Herlev Gentofte Univ Hosp, Dept Cardiol, Copenhagen, Denmark
[3] Univ Alberta, Div Infect Dis, Edmonton, AB, Canada
[4] Hosp Clin Barcelona, Infect Dis Dept, Villarroel 170, Barcelona 08036, Spain
[5] Vall dHebron Inst Res VHIR, Barcelona, Spain
关键词
Bacteraemia; Bundles; Echocardiography; Enterococci; High-level aminoglycoside resistance vancomycin-resistance; BLOOD-STREAM INFECTIONS; QUALITY-OF-CARE; ANTIMICROBIAL THERAPY; VANCOMYCIN-RESISTANT; RISK-FACTORS; ENDOCARDITIS; MORTALITY; IMPACT; INTERVENTION; PREVALENCE;
D O I
10.1016/j.cmi.2020.10.029
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: Enterococcal bacteraemia (EB) is common, particularly in the nosocomial setting, and its management poses a challenge for clinicians and microbiologists. Objectives: The aim was to summarize the more relevant features of EB and to provide a practical state-of-the-art on the topics that more directly affect its management. Sources: Pubmed articles from inception to 31 May 2020. Content: The following topics are covered: epidemiological, clinical and microbiological characteristics and factors associated with prognosis of EB; diagnosis and work-up, including the use of echocardiography to rule out endocarditis; antibiotic management with special focus on antimicrobial resistance and complicated EB; and the role of infectious disease consultation and the use of bundles in EB. In addition, three clinical vignettes are presented to illustrate the practical application of the guidance provided, and major gaps in the current evidence supporting EB management are discussed. (C) 2020 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:364 / 371
页数:8
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