Contribution of Android and Gynoid Adiposity to Bone Mineral Density in Healthy Postmenopausal Thai Women

被引:10
作者
Namwongprom, Sirianong [1 ,2 ]
Rojanasthien, Sattaya [3 ]
Wongboontan, Chanpen [2 ]
Mangklabruks, Ampica [4 ]
机构
[1] Chiang Mai Univ, Fac Med, Clin Epidemiol Program, Chiang Mai, Thailand
[2] Chiang Mai Univ, Fac Med, Dept Radiol, Chiang Mai 50200, Thailand
[3] Chiang Mai Univ, Fac Med, Dept Orthopaed, Chiang Mai, Thailand
[4] Chiang Mai Univ, Fac Med, Dept Internal Med, Chiang Mai, Thailand
关键词
Android adiposity; android fat mass; bone mineral density; gynoid adiposity; gynoid fat mass; FAT MASS; BODY-COMPOSITION; VISCERAL FAT; LEAN MASS; ASSOCIATIONS; FRACTURES; OBESITY; MEN;
D O I
10.1016/j.jocd.2018.05.037
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Dual-energy X-ray absorptiometry (DXA) is one of the major tools for assessing the whole body and regional body composition and body adiposity. Various body composition parameters including android fat mass (AFM), gynoid fat mass (GFM), and android-to-gynoid fat ratio (AG fat ratio) obtained from whole body DXA can be used as a reliable surrogate marker for regional body composition analysis. This study aimed to explore the contribution of android and gynoid adiposity to bone mineral density (BMD) in healthy postmenopausal Thai women. This cross-sectional study enrolled 1448 healthy Thai women, ages 40-90 without medication history or known disease affecting the BMD. Lumbar spine (LS), total femur, and femoral neck BMDs, AFM, GFM, and AG fat ratio were measured by DXA. To evaluate the contribution of android and gynoid adiposity with various measures of BMDs, univariable and multivariable linear regression analyses were used to estimate the regression coefficients. AFM, GFM, and AG fat ratio had a significant positive association with BMD of all measured sites (p < 0.001) in the univariate analysis. The strongest association was found between AG fat ratio and LS BMD (beta = 0.156, p <= 0.001). In multivariate linear regression analysis, the results continued to show a positive association between AFM and GFM at all skeletal sites after adjusting for age, height, and total body lean mass. Relationship between AG fat ratio and BMD was found only in LS region. GFM had a strongest positive effect with BMD at the LS, total femur, and femoral neck regions. Higher android and gynoid adiposity was associated with higher BMD. GFM rather than AFM shows the strongest positive association with BMDs in postmenopausal Thai women.
引用
收藏
页码:346 / 350
页数:5
相关论文
共 20 条
[1]   Different Relationships Between Body Compositions and Bone Mineral Density According to Gender and Age in Korean Populations (KNHANES 2008-2010) [J].
Ahn, Seong Hee ;
Lee, Seung Hun ;
Kim, Hyeonmok ;
Kim, Beom-Jun ;
Koh, Jung-Min .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (10) :3811-3820
[2]   Relationship Between Visceral Adiposity and Bone Mineral Density in Korean Adults [J].
Choi, Han Seok ;
Kim, Kwang Joon ;
Kim, Kyoung Min ;
Hur, Nam Wook ;
Rhee, Yumie ;
Han, Dae Suk ;
Lee, Eun Jig ;
Lim, Sung-Kil .
CALCIFIED TISSUE INTERNATIONAL, 2010, 87 (03) :218-225
[3]   Contributions of fat mass and fat distribution to hip bone strength in healthy postmenopausal Chinese women [J].
Da Shao, Hong ;
Li, Guan Wu ;
Liu, Yong ;
Qiu, Yu You ;
Yao, Jian Hua ;
Tang, Guang Yu .
JOURNAL OF BONE AND MINERAL METABOLISM, 2015, 33 (05) :507-515
[4]   Relationship between body fat distribution and bone mineral density in premenopausal Japanese women [J].
Douchi, T ;
Yamamoto, S ;
Oki, T ;
Maruta, K ;
Kuwahata, R ;
Nagata, Y .
OBSTETRICS AND GYNECOLOGY, 2000, 95 (05) :722-725
[5]   Visceral fat adipokine secretion is associated with systemic inflammation in obese humans [J].
Fontana, Luigi ;
Eagon, J. Christopher ;
Trujillo, Maria E. ;
Scherer, Philipp E. ;
Klein, Samuel .
DIABETES, 2007, 56 (04) :1010-1013
[6]   Associations of fat mass and fat distribution with bone mineral density in pre- and postmenopausal Chinese women [J].
Fu, X. ;
Ma, X. ;
Lu, H. ;
He, W. ;
Wang, Z. ;
Zhu, S. .
OSTEOPOROSIS INTERNATIONAL, 2011, 22 (01) :113-119
[7]   The Associations of Body Composition and Fat Distribution With Bone Mineral Density in Elderly Italian Men and Women [J].
Gonnelli, Stefano ;
Caffarelli, Carla ;
Tanzilli, Loredana ;
Alessi, Chiara ;
Pitinca, Maria Dea Tomai ;
Rossi, Stefania ;
Campagna, Maria Stella ;
Nuti, Ranuccio .
JOURNAL OF CLINICAL DENSITOMETRY, 2013, 16 (02) :168-177
[8]  
Hsu YH, 2006, AM J CLIN NUTR, V83, P146
[9]   Fat mass is not beneficial to bone in adolescents and young adults [J].
Janicka, Agnieszka ;
Wren, Tishya A. L. ;
Sanchez, Monique M. ;
Dorey, Frederick ;
Kim, Paul S. ;
Mittelman, Steven D. ;
Gilsanz, Vicente .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (01) :143-147
[10]   Relationship between body composition and bone mineral density (BMD) in perimenopausal Korean women [J].
Kim, C. J. ;
Oh, K. W. ;
Rhee, E. J. ;
Kim, K. H. ;
Jo, S. K. ;
Jung, C. H. ;
Won, J. C. ;
Park, C. Y. ;
Lee, W. Y. ;
Park, S. W. ;
Kim, S. W. .
CLINICAL ENDOCRINOLOGY, 2009, 71 (01) :18-26