Pediatric Neuroendocrine Carcinoid Tumors: Review of Diagnostic Imaging Findings and Recent Advances

被引:10
作者
Degnan, Andrew J. [1 ,2 ,3 ]
Tadros, Sameh S. [1 ,2 ,3 ]
Tocchio, Shannon [4 ]
机构
[1] Univ Pittsburgh, Dept Radiol, Med Ctr, Pittsburgh, PA 15260 USA
[2] Univ Pittsburgh, Childrens Hosp Pittsburgh, Dept Pediat Radiol, Pittsburgh, PA 15213 USA
[3] Univ Pittsburgh, Sch Med, Dept Radiol, Pittsburgh, PA USA
[4] Univ Virginia Hlth Syst, Dept Radiol & Med Imaging, POB 800170, Charlottesville, VA 22908 USA
关键词
carcinoid tumor; diagnostic imaging; MRI; neuroendocrine tumor; octreotide; pediatric radiology; SOMATOSTATIN RECEPTOR SCINTIGRAPHY; PRIMARY MALIGNANT-TUMORS; SMALL-BOWEL NEOPLASMS; OF-THE-LITERATURE; CT-ENTEROCLYSIS; OCTREOTIDE SCINTIGRAPHY; RADIONUCLIDE THERAPY; RADIOGUIDED SURGERY; CLINICAL-FEATURES; CUSHINGS-SYNDROME;
D O I
10.2214/AJR.16.17287
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
OBJECTIVE. Although rare, pediatric neuroendocrine tumors including carcinoid tumor have increased in incidence over the past few decades. Despite increased recognition, survival rates have not significantly improved. Earlier detection of these tumors is necessary to improve clinical outcomes. This article discusses imaging approaches for detecting pediatric carcinoid tumors including anatomic imaging methods such as CT and MRI as well as functional imaging methods targeting the somatostatin receptor including In-111-labeled octreotide and newer Ga-68-based radiotracers that may hold promise in hybrid PET/CT or PET/MRI. CONCLUSION. Improvements in functional imaging with novel somatostatin receptor-specific radiotracers along with fused functional and anatomic imaging have substantially improved the clinical detection of carcinoid tumors. Although rare, these tumors are encountered in children, and an awareness of the appropriate use of various imaging methods is essential for pediatric specialists. Further research is needed to ascertain the diagnostic value of newer imaging methods and radiotracer-based treatment approaches, especially in the pediatric population.
引用
收藏
页码:881 / 890
页数:10
相关论文
共 50 条
  • [31] Pediatric head trauma: an extensive review on imaging requisites and unique imaging findings
    F. C. Sarioglu
    H. Sahin
    Y. Pekcevik
    O. Sarioglu
    O. Oztekin
    European Journal of Trauma and Emergency Surgery, 2018, 44 : 351 - 368
  • [32] Pediatric head trauma: an extensive review on imaging requisites and unique imaging findings
    Sarioglu, F. C.
    Sahin, H.
    Pekcevik, Y.
    Sarioglu, O.
    Oztekin, O.
    EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY, 2018, 44 (03) : 351 - 368
  • [33] Primary solid pancreatic tumors: recent imaging findings updates with pathology correlation
    So Yeon Kim
    Seong Ho Park
    Nurhee Hong
    Jin Hee Kim
    Seung-Mo Hong
    Abdominal Imaging, 2013, 38 : 1091 - 1105
  • [34] MR imaging findings of parotid tumors with pathologic diagnostic clues - A pictorial essay
    Kinoshita, T
    Ishii, K
    Naganuma, H
    Okitsu, T
    CLINICAL IMAGING, 2004, 28 (02) : 93 - 101
  • [35] Diagnostic accuracy of endoscopic ultrasound in pancreatic neuroendocrine tumors: A systematic review and meta analysis
    Puli, Srinivas R.
    Kalva, Nikhil
    Bechtold, Matthew L.
    Pamulaparthy, Smitha R.
    Cashman, Micheal D.
    Estes, Norman C.
    Pearl, Richard H.
    Volmar, Fritz-Henry
    Dillon, Sonu
    Shekleton, Michael F.
    Forcione, David
    WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 19 (23) : 3678 - 3684
  • [36] Diagnostic, Surgical, and Postoperative Challenges of Neuroendocrine Tumors of the Neck: Clinical Experience and Literature Review
    Khan, Mohammad Mussadaq
    Khan, Mohammad Iqbal
    Ali, Hussan
    Kazmi, Tehreem
    Iqbal, Hania
    ANNALS OF VASCULAR SURGERY, 2017, 45 : 92 - 97
  • [37] Immunoglobulin G4-Related Disease: Recent Advances in Pathogenesis and Imaging Findings
    Katabathina, Venkata S.
    Khalil, Suhare
    Shin, Sooyoung
    Lath, Narayan
    Menias, Christine O.
    Prasad, Srinivasa R.
    RADIOLOGIC CLINICS OF NORTH AMERICA, 2016, 54 (03) : 535 - +
  • [38] Artificial Intelligence in Spinal Imaging and Patient Care: A Review of Recent Advances
    Lee, Sungwon
    Jung, Joon-Yong
    Mahatthanatrakul, Akaworn
    Kim, Jin-Sung
    NEUROSPINE, 2024, 21 (02) : 474 - 486
  • [39] Peptide receptor imaging in neuroendocrine tumors: comparison between diagnostic scintigraphy and post-therapy whole-body scan
    Fabio Minutoli
    Astrid Herberg
    Alessandro Sindoni
    Davide Cardile
    Mariapaola Cucinotta
    Sergio Baldari
    Annals of Nuclear Medicine, 2013, 27 : 654 - 660
  • [40] Imaging of pediatric testicular tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper
    Behr, Gerald G.
    Morani, Ajaykumar C.
    Artunduaga, Maddy
    Desoky, Sarah M.
    Epelman, Monica
    Friedman, Jonathan
    Lala, Shailee, V
    Seekins, Jayne
    Towbin, Alexander J.
    Back, Susan J.
    PEDIATRIC BLOOD & CANCER, 2023, 70